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NCT06487624 · ClinicalTrials.gov registry record · Phase 1
An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors
A Phase 1 study of Advanced Solid Tumor and Refractory Hodgkin Lymphoma, sponsored by FBD Biologics Limited.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 50
- Enrollment target
- 6
- Study locations
NCT06487624 is a Phase 1 study of Advanced Solid Tumor and Refractory Hodgkin Lymphoma that is actively recruiting participants, run by FBD Biologics Limited. The registered enrollment target is 50 participants, below the 193-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (74% lower). The trial reports 6 study locations across 2 states.
The verdict
NCT06487624, a Phase 1 study of Advanced Solid Tumor and Refractory Hodgkin Lymphoma, is actively recruiting participants, sponsored by FBD Biologics Limited.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 50 participants
- Enrollment target
- 6
- Study locations
Study Summary
The purpose of this study is to find out whether IV injection of HCB301 is an effective treatment for different types of advanced solid tumors and relapsed and refractory classical Hodgkin lymphomas and what side effects (unwanted effects) may occur in subjects aged 18 years old and above.
Conditions Studied
Interventions
- DRUG HCB301
Study Locations (6)
Other
- The First Affiliated Hospital, Zhejiang University School of Medicine - Hangzhou
- Zhejiang Provincial Cancer Hospital - Hangzhou
- Xuzhou Central Hospital - Xuzhou
- Yantai Yuhuangding Hospital - Yantai
- Southern Medical University Zhujiang Hospital - Zhujiang
South Carolina
- Prisma Health-Upstate - Greenville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2025-04-02 |
| Est. Completion | 2027-05-31 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06487624
The ClinicalTrials.gov registry entry for NCT06487624 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 193-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (74% lower). The listed sponsor is FBD Biologics Limited, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Advanced Solid Tumor appearing as the primary indexed condition, and to 1 intervention - of which HCB301 is the first listed.
NCT06487624 reports 6 study locations spanning 2 distinct geographic areas - top geographies include Other, South Carolina.
Frequently Asked Questions
What is clinical trial NCT06487624 about?
NCT06487624 is a clinical study titled "An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors". The purpose of this study is to find out whether IV injection of HCB301 is an effective treatment for different types of advanced solid tumors and relapsed and refractory classical Hodgkin lymphomas and what side effects (unwanted effects) may occur in subjects aged 18 years old and above.
What is the current status of trial NCT06487624?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2025-04-02. Estimated completion is 2027-05-31.
What conditions does trial NCT06487624 study?
This clinical trial studies the following conditions: Advanced Solid Tumor, Refractory Hodgkin Lymphoma.
What interventions are being tested in trial NCT06487624?
The interventions under investigation include: HCB301 (DRUG).
Who is sponsoring clinical trial NCT06487624?
This trial is sponsored by FBD Biologics Limited, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06487624 being conducted?
This trial has 6 study locations across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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