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NCT06474754 · ClinicalTrials.gov registry record · NA
Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery
A NA study of Myocardial Injury After Non-cardiac Surgery and Submaximal Exercise Performance, sponsored by Yale University.
- Recruiting
- Registry status
- NA
- Development phase
- 61
- Enrollment target
- 1
- Study location
NCT06474754: Recruiting NA study of Myocardial Injury After Non-cardiac Surgery and Submaximal Exercise Performance, sponsored by Yale University.
NCT06474754 is a NA study of Myocardial Injury After Non-cardiac Surgery and Submaximal Exercise Performance that is actively recruiting participants, run by Yale University. The registered enrollment target is 61 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06474754, a NA study of Myocardial Injury After Non-cardiac Surgery and Submaximal Exercise Performance, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- NA
- Development phase
- 61 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn whether physicians can associate evidence of myocardial injury after surgery with findings obtained from submaximal cardiopulmonary exercise testing. The main questions are: Is detection of postoperative myocardial injury with submaximal cardiopulmonary exercise testing superior to using usual care? And which submaximal cardiopulmonary exercise testing measure is better? Participants will undergo evaluation with a short submaximal cardiopulmonary exercise test, then undergo surgery. Myocardial injury will be measured on postoperative days 0, 1, 2, and 3 (during and up to 3 days after surgery). These results will analyzed by comparing it to findings from the submaximal cardiopulmonary exercise test. If there is a relationship, this will help anesthesiologists and surgeons assign certain treatments that may reduce the risk of developing myocardial injury after surgery.
Primary Outcome
Myocardial Injury after noncardiac surgery. Measurement: High-Sensitivity Troponin assay with an abnormal value defined as 14 nanograms per liter or greater.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST High-sensitivity troponin, serum
- DIAGNOSTIC_TEST Submaximal Cardiopulmonary Exercise Testing
- DIAGNOSTIC_TEST Duke Activity Status Index
Study Locations (1)
Connecticut
- Yale University; Yale New Haven Hospital - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2025-03-30 |
| Est. Completion | 2027-01-31 |
| Phase | NA |
What NCT06474754 shows while recruiting
NCT06474754 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 3 conditions, with Myocardial Injury After Non-cardiac Surgery appearing as the primary indexed condition, and to 3 interventions - of which High-sensitivity troponin, serum is the first listed.
NCT06474754 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT06474754 about?
NCT06474754 is a clinical study titled "Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery". The goal of this clinical trial is to learn whether physicians can associate evidence of myocardial injury after surgery with findings obtained from submaximal cardiopulmonary exercise testing. The main questions are: Is detection of postoperative myocardial injury with submaximal cardiopulmonary e...
What is the current status of trial NCT06474754?
This trial is currently recruiting. It is a NA study. The enrollment target is 61 participants. The study started on 2025-03-30. Estimated completion is 2027-01-31.
What conditions does trial NCT06474754 study?
This clinical trial studies the following conditions: Myocardial Injury After Non-cardiac Surgery, Submaximal Exercise Performance, Preoperative Period.
What interventions are being tested in trial NCT06474754?
The interventions under investigation include: High-sensitivity troponin, serum (DIAGNOSTIC_TEST), Submaximal Cardiopulmonary Exercise Testing (DIAGNOSTIC_TEST), Duke Activity Status Index (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06474754?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06474754 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT06474754's enrollment target sits among peer trials
61 1164th of 2000 higher than 837 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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