Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06467448 · ClinicalTrials.gov registry record

Comparing Train-of-Four Recovery in the Adductor Pollicis Versus the Adductor Digiti Minimi in Elective Surgery Patients

A clinical trial, sponsored by University of North Carolina, Chapel Hill.

Completed
Registry status
57
Enrollment target

NCT06467448: Completed study, sponsored by University of North Carolina, Chapel Hill.

NCT06467448 is a clinical trial that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 57 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06467448 has completed, sponsored by University of North Carolina, Chapel Hill.

COMPLETED
Registry status
57 participants
Enrollment target

Study Summary

The train-of-four (TOF) ratio is a quantitative measure used in anesthesia to assess the degree of neuromuscular blockade induced by neuromuscular blocking agents during surgical procedures. Current American Society of Anesthesiologists guidelines recommend monitoring the TOF ratio to guide the administration and reversal of NMBAs, with a target ratio of 0.9 or higher at adductor pollicis muscle indicating adequate reversal and restoration of neuromuscular function. This proposed study aims to observe and compare the TOF ratio between two different muscles of the hand: adductor pollicis and adductor digiti minim using anesthesia monitors on both of their arms during recovery of neuromuscular function. Surgery and anesthesia will occur per standard of care.

Primary Outcome

The train of four ratio at the digiti minimi will be recorded when the adductor pollicis ratio reads 90 percent

Interventions

  • DEVICE EMG Assessement of Recovery of Neuromuscular Function

Trial Details

FieldValue
Enrollment Target 57 participants
Start Date 2024-03-18
Est. Completion 2025-06-01

What the finished NCT06467448 record still lists

NCT06467448 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 57 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which EMG Assessement of Recovery of Neuromuscular Function is the first listed.

NCT06467448 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06467448 about?

NCT06467448 is a clinical study titled "Comparing Train-of-Four Recovery in the Adductor Pollicis Versus the Adductor Digiti Minimi in Elective Surgery Patients". The train-of-four (TOF) ratio is a quantitative measure used in anesthesia to assess the degree of neuromuscular blockade induced by neuromuscular blocking agents during surgical procedures. Current American Society of Anesthesiologists guidelines recommend monitoring the TOF ratio to guide the admi...

What is the current status of trial NCT06467448?

This trial is currently completed. The enrollment target is 57 participants. The study started on 2024-03-18. Estimated completion is 2025-06-01.

What interventions are being tested in trial NCT06467448?

The interventions under investigation include: EMG Assessement of Recovery of Neuromuscular Function (DEVICE).

Who is sponsoring clinical trial NCT06467448?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03521830 · 57 participants · Phase 2

    Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic Basal Cell Carcinoma

  • NCT03587701 · 57 participants · Phase 2

    Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease

  • NCT04104126 · 57 participants · NA

    Blood Flow Restriction Therapy in Achilles Injury

  • NCT04703842 · 57 participants · Phase 1

    Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT06467448, the US trial registry maintained by the National Library of Medicine. NCT06467448 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.