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NCT06466655 · ClinicalTrials.gov registry record · NA
Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline
A NA study, sponsored by University of Delaware.
- Completed
- Registry status
- NA
- Development phase
- 17
- Enrollment target
NCT06466655: Completed NA study, sponsored by University of Delaware.
NCT06466655 is a NA study that has completed, run by University of Delaware. The registered enrollment target is 17 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06466655, a NA study, has completed, sponsored by University of Delaware.
- COMPLETED
- Registry status
- NA
- Development phase
- 17 participants
- Enrollment target
Study Summary
The goal of this pilot clinical trial is to begin to understand how day-to-day stress affects cardiovascular health and brain function in middle-aged adults. The main question aims to answer is whether the link between daily stress and vascular dysfunction is a potential mechanism of increased risk for future cognitive decline. Participants will complete a 15-day testing cycle. During this cycle, participants will complete daily assessments of stress using an online survey tool for 14-consecutive days. On the last day of each cycle, vascular function will be assessed during a laboratory visit.
Primary Outcome
NO-mediated EDD will be calculated as the relative difference (%) in dilation from the local heating-induced plateau to the post-L-NAME plateau after scavenging mitochondrial-derived superoxide
Interventions
- DRUG MitoTempol
- DRUG Lactated Ringer's (control)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2024-05-30 |
| Est. Completion | 2025-05-29 |
| Phase | NA |
What the finished NCT06466655 record still lists
NCT06466655 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which MitoTempol is the first listed.
NCT06466655 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06466655 about?
NCT06466655 is a clinical study titled "Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline". The goal of this pilot clinical trial is to begin to understand how day-to-day stress affects cardiovascular health and brain function in middle-aged adults. The main question aims to answer is whether the link between daily stress and vascular dysfunction is a potential mechanism of increased risk ...
What is the current status of trial NCT06466655?
This trial is currently completed. It is a NA study. The enrollment target is 17 participants. The study started on 2024-05-30. Estimated completion is 2025-05-29.
What interventions are being tested in trial NCT06466655?
The interventions under investigation include: MitoTempol (DRUG), Lactated Ringer's (control) (DRUG).
Who is sponsoring clinical trial NCT06466655?
This trial is sponsored by University of Delaware, which has 106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06466655's enrollment target sits among peer trials
17 1871st of 2000 higher than 130 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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