Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06465979 · ClinicalTrials.gov registry record · NA
Perception of Speech in Context by Listeners With Healthy and Impaired Hearing
A NA study of Hearing Loss and Hearing, sponsored by Marquette University.
- Recruiting
- Registry status
- NA
- Development phase
- 680
- Enrollment target
- 2
- Study locations
NCT06465979: Recruiting NA study of Hearing Loss and Hearing, sponsored by Marquette University.
NCT06465979 is a NA study of Hearing Loss and Hearing that is actively recruiting participants, run by Marquette University. The registered enrollment target is 680 participants, below the 6,109-participant average among 58 other Hearing Loss trials with a reported enrollment target (89% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06465979, a NA study of Hearing Loss and Hearing, is actively recruiting participants, sponsored by Marquette University.
- RECRUITING
- Registry status
- NA
- Development phase
- 680 participants
- Enrollment target
- 2
- Study locations
Study Summary
Recognition of speech sounds is accomplished through the use of adjacent sounds in time, in what is termed acoustic context. The frequency and temporal properties of these contextual sounds play a large role in recognition of human speech. Historically, most research on both speech perception and sound perception in general examine sounds out-of-context, or presented individually. Further, these studies have been conducted independently of each other with little connection across labs, across sounds, etc. These approaches slow the progress in understanding how listeners with hearing difficulties use context to recognize speech and how their hearing aids and/or cochlear implants might be modified to improve their perception. This research has three main goals. First, the investigators predict that performance in speech sound recognition experiments will be related when testing the same speech frequencies or the same moments in time, but that performance will not be related in further comparisons across speech frequencies or at different moments in time. Second, the investigators predict that adding background noise will make this contextual speech perception more difficult, and that these difficulties will be more severe for listeners with hearing loss. Third, the investigators predict that cochlear implant users will also use surrounding sounds in their speech recognition, but with key differences than healthy-hearing listeners owing to the sound processing done by their implants. In tandem with these goals, the investigators will use computer models to simulate how neurons respond to speech sounds individually and when surrounded by other sounds.
Primary Outcome
The participant sits inside a double-walled sound booth. They are seated at a table that contains a computer monitor and a mouse. A single utterance is played over headphones or through a loudspeaker directly in front, and the participant indicates what they thought the utterance was by selecting among various options on the screen using the mouse. During a single block of trials there are between 60 and 160 sounds, depending on the exact experiment. Ordering of stimuli within the block is rando
Conditions Studied
Interventions
- BEHAVIORAL Speech Manipulation
Study Locations (2)
Minnesota
- University of Minnesota - Minneapolis
Wisconsin
- Marquette University - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 680 participants |
| Start Date | 2023-09-19 |
| Est. Completion | 2027-08-31 |
| Phase | NA |
What NCT06465979 shows while recruiting
NCT06465979 is an interventional study that assigns participants to a tested intervention. The registered 680 participants enrollment target is mid-sized for trials with a published cap, below the 6,109-participant average among 58 other Hearing Loss trials with a reported enrollment target (89% lower).
The record links to 2 conditions, with Hearing Loss appearing as the primary indexed condition, and to 1 intervention - of which Speech Manipulation is the first listed.
NCT06465979 reports a single indexed study location in Minnesota, Wisconsin.
Frequently Asked Questions
What is clinical trial NCT06465979 about?
NCT06465979 is a clinical study titled "Perception of Speech in Context by Listeners With Healthy and Impaired Hearing". Recognition of speech sounds is accomplished through the use of adjacent sounds in time, in what is termed acoustic context. The frequency and temporal properties of these contextual sounds play a large role in recognition of human speech. Historically, most research on both speech perception and so...
What is the current status of trial NCT06465979?
This trial is currently recruiting. It is a NA study. The enrollment target is 680 participants. The study started on 2023-09-19. Estimated completion is 2027-08-31.
What conditions does trial NCT06465979 study?
This clinical trial studies the following conditions: Hearing Loss, Hearing.
What interventions are being tested in trial NCT06465979?
The interventions under investigation include: Speech Manipulation (BEHAVIORAL).
Who is sponsoring clinical trial NCT06465979?
This trial is sponsored by Marquette University, which has 27 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06465979 being conducted?
This trial has 2 study locations across Minnesota, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hearing Loss
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06465979's enrollment target sits among peer trials
680 10th of 58 higher than 49 of 58 other Hearing Loss trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hearing Loss trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Improving Access and Affordability of Adult Hearing Healthcare
RECRUITING · NA
-
AI Noise Reduction in Phonak Hearing Aids
RECRUITING · NA
-
Investigation of a Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation
RECRUITING · NA
-
Auditory-Cognitive Training to Optimize Outcomes for Older CI Users
RECRUITING · NA
-
Innovations in Hearing Accessibility and Technology (IHAT) Study
RECRUITING · NA
-
Clinical Utility of Residual Hearing in the Cochlear Implant Ear
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03501706 · 680 participants · NA
An Assessment of Cognitive Improvement Training Among Mid-life Individuals
- NCT05626452 · 680 participants · NA
PrEP Optimization Among Women to Enhance Retention and Uptake
- NCT05753748 · 680 participants · NA
Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia
- NCT05952141 · 680 participants · NA
Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI