Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Lumbar Spine Degeneration: later-stage trial registry
4 of 8 indexed Lumbar Spine Degeneration trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 4 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Lumbar Spine Degeneration: 8 US clinical trials tracked, 4 recruiting.
Lumbar Spine Degeneration is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is 3Spine, running 2 of these trials.
Enrollment posture brief
Registry condition lumbar-spine-degeneration
OPEN 4 | RECR 50% | LATE 2 | EARLY 1 | RANK #2176 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Lumbar Spine Degeneration lists 4 open slots (50% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Lumbar Spine Degeneration on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Lumbar Spine Degeneration is recruiting above its size-band peers.
4 of 8 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Lumbar Spine Degeneration research.
3Spine accounts for 2 of 8 trials (25%). 7 distinct sponsors appear on at least one study for this condition label.
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Typical Lumbar Spine Degeneration enrolment sits around 176 participants.
Median target enrolment is 176 among the 8 trials that report a genuine target (sentinel values excluded). 2 of those (25%) plan for fewer than 100 participants.
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Lumbar Spine Degeneration splits between interventional and observational designs.
5 interventional and 3 observational studies make up this index (62.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
OpalGenix- Personalized Postoperative Pain Management Following Lumbar Spinal Fusion and Decompression Surgery in Adults
OpalGenix
NCT05452694
The NOTICE Study: Neurosurgery and OrThopedIcs Communication Evaluation Study Following Lumbar Fusions
Duke University
NCT04140344
The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion
University of Southern California
NCT05746143
LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF)
Locate Bio Pty
NCT06462729
Comparison of Complication Rates Between Initial and Re-operative Anterior Lumbar Interbody Fusion Surgery: Is There a Difference?
Methodist Health System
NCT05945550
3Spine Lumbar Fusion Real World Evidence Study
3Spine
NCT04823858
MOTUS Total Joint Replacement Investigational Device Exemption Study
3Spine
NCT05438719
A Randomized Trial of Exparel vs Saline in Opioid Reduction of Pain Management Following Lumbar Spine Surgeries.
University of Missouri-Columbia
NCT04644796
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Lumbar Spine Degeneration records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Lumbar Spine Degeneration trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Lumbar Spine Degeneration page
8 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Lumbar Spine Degeneration trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- 3Spine sponsors the most Lumbar Spine Degeneration trials on record, review their full trial history before evaluating a specific study. See 3Spine's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Lumbar Spine Degeneration condition card totals 8 registered trials; most-linked intervention MOTUS Total Joint Replacement; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.