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NCT06455527 · ClinicalTrials.gov registry record · NA
Heart Rate Variability (HRV)-Guided Transcranial Direct Current Stimulation (tDCS)
A NA study of Depression, sponsored by NYU Langone Health.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06455527: Recruiting NA study of Depression, sponsored by NYU Langone Health.
NCT06455527 is a NA study of Depression that is actively recruiting participants, run by NYU Langone Health. The registered enrollment target is 100 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06455527, a NA study of Depression, is actively recruiting participants, sponsored by NYU Langone Health.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This technology development project will be informed and guided by initial data collection of human subject data. For this purpose, the investigators will recruit n=100 people with mild to moderate depression in a double-blinded, parallel-arm, sham-controlled data collection period administered at home and using the investigator's remotely supervised (RS) tDCS protocol. Enrolled participants will complete 10 days of 30-minute tDCS (2.0, DLPFC left anodal) using the RS-tDCS protocol. During each daily session, standard HR and impedance-based HR (i-HR), obtained from the tDCS headset, will be collected to identify a possible marker of response to tDCS in depression. Participants will be randomized 2:1 to active vs. sham tDCS.
Primary Outcome
HR will be measured using Polar H10 Chest Monitor at each daily tDCS session.
Conditions Studied
Interventions
- DEVICE Sham Transcranial Direct Current Stimulation (tDCS)
- DEVICE Active Transcranial Direct Current Stimulation (tDCS)
Study Locations (1)
New York
- NYU Langone Health - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-01-02 |
| Est. Completion | 2027-11-01 |
| Phase | NA |
What NCT06455527 shows while recruiting
NCT06455527 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 786-participant average among 679 other Depression trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Sham Transcranial Direct Current Stimulation (tDCS) is the first listed.
NCT06455527 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT06455527 about?
NCT06455527 is a clinical study titled "Heart Rate Variability (HRV)-Guided Transcranial Direct Current Stimulation (tDCS)". This technology development project will be informed and guided by initial data collection of human subject data. For this purpose, the investigators will recruit n=100 people with mild to moderate depression in a double-blinded, parallel-arm, sham-controlled data collection period administered at h...
What is the current status of trial NCT06455527?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2025-01-02. Estimated completion is 2027-11-01.
What conditions does trial NCT06455527 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT06455527?
The interventions under investigation include: Sham Transcranial Direct Current Stimulation (tDCS) (DEVICE), Active Transcranial Direct Current Stimulation (tDCS) (DEVICE).
Who is sponsoring clinical trial NCT06455527?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06455527 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06455527's enrollment target sits among peer trials
100 326th of 679 higher than 331 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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