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NCT06447506 · ClinicalTrials.gov registry record · Phase 2

Long-Term Study (AtDvance) to Evaluate GSK1070806 in Atopic Dermatitis.

A Phase 2 study, sponsored by GlaxoSmithKline.

Terminated
Registry status
Phase 2
Development phase
79
Enrollment target

NCT06447506: Clinical Trial Phase 2 study, sponsored by GlaxoSmithKline.

NCT06447506 is a Phase 2 study that was terminated before completion, run by GlaxoSmithKline. The registered enrollment target is 79 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (41% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06447506, a Phase 2 study, was terminated before completion, sponsored by GlaxoSmithKline.

TERMINATED
Registry status
Phase 2
Development phase
79 participants
Enrollment target

Study Summary

The study is designed to evaluate the long-term safety and efficacy of GSK1070806 in participants with moderate-to severe atopic dermatitis, who have completed phase 2b parent GSK atopic dermatitis (AtD) study (NCT05999799).

Primary Outcome

An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of a study intervention, whether or not considered related to the study intervention. A TEAE is an event that emerges during treatment, having been absent pre-treatment or worsens relative to the pre-treatment state. Safety Analysis Set included all assigned participants who received at least 1 dose of study intervention in this LTE study. Participants were analyzed according to the inter

Interventions

  • DRUG Placebo
  • DRUG GSK1070806

Trial Details

FieldValue
Enrollment Target 79 participants
Start Date 2024-06-05
Est. Completion 2025-07-29
Phase Phase 2
GlaxoSmithKline

1,345 total trials

Why NCT06447506 stopped before completion

NCT06447506 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 79 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (41% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT06447506 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06447506 about?

NCT06447506 is a clinical study titled "Long-Term Study (AtDvance) to Evaluate GSK1070806 in Atopic Dermatitis.". The study is designed to evaluate the long-term safety and efficacy of GSK1070806 in participants with moderate-to severe atopic dermatitis, who have completed phase 2b parent GSK atopic dermatitis (AtD) study (NCT05999799).

What is the current status of trial NCT06447506?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 79 participants. The study started on 2024-06-05. Estimated completion is 2025-07-29.

What interventions are being tested in trial NCT06447506?

The interventions under investigation include: Placebo (DRUG), GSK1070806 (DRUG).

Who is sponsoring clinical trial NCT06447506?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06447506's enrollment target sits among peer trials

79 884th of 2000 higher than 1,117 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06447506, the US trial registry maintained by the National Library of Medicine. NCT06447506 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.