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NCT06439485 · ClinicalTrials.gov registry record · Phase 1

Phase I/II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion

A Phase 1 study of Advanced Cholangiocarcinoma and FGFR2 Fusion, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 1
Development phase
25
Enrollment target
1
Study location

NCT06439485 is a Phase 1 study of Advanced Cholangiocarcinoma and FGFR2 Fusion that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 25 participants, below the 114-participant average among 3 other Advanced Cholangiocarcinoma trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06439485, a Phase 1 study of Advanced Cholangiocarcinoma and FGFR2 Fusion, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 1
Development phase
25 participants
Enrollment target
1
Study location

Study Summary

To learn if pemigatinib in combination with atezolizumab and bevacizumab can help to control cholangiocarcinoma.

Interventions

  • DRUG Bevacizumab
  • DRUG Atezolizumab
  • DRUG Pemigatinib

Study Locations (1)

Texas

  • MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2024-11-19
Est. Completion 2030-02-22
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT06439485

The ClinicalTrials.gov registry entry for NCT06439485 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 114-participant average among 3 other Advanced Cholangiocarcinoma trials with a reported enrollment target (78% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Advanced Cholangiocarcinoma appearing as the primary indexed condition, and to 3 interventions - of which Bevacizumab is the first listed.

NCT06439485 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT06439485 about?

NCT06439485 is a clinical study titled "Phase I/II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion". To learn if pemigatinib in combination with atezolizumab and bevacizumab can help to control cholangiocarcinoma.

What is the current status of trial NCT06439485?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2024-11-19. Estimated completion is 2030-02-22.

What conditions does trial NCT06439485 study?

This clinical trial studies the following conditions: Advanced Cholangiocarcinoma, FGFR2 Fusion.

What interventions are being tested in trial NCT06439485?

The interventions under investigation include: Bevacizumab (DRUG), Atezolizumab (DRUG), Pemigatinib (DRUG).

Who is sponsoring clinical trial NCT06439485?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06439485 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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