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NCT06428500 · ClinicalTrials.gov registry record · Phase 1

QTX3046 in Patients With KRAS G12D Mutations

A Phase 1 study of Advanced Solid Tumor, sponsored by Quanta Therapeutics.

Active
Registry status
Phase 1
Development phase
240
Enrollment target
5
Study locations

NCT06428500 is a Phase 1 study of Advanced Solid Tumor that is active but no longer recruiting, run by Quanta Therapeutics. The registered enrollment target is 240 participants, above the 192-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (25% higher). The trial reports 5 study locations across 4 states.

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The verdict

NCT06428500, a Phase 1 study of Advanced Solid Tumor, is active but no longer recruiting, sponsored by Quanta Therapeutics.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
240 participants
Enrollment target
5
Study locations

Study Summary

Phase 1 study to determine the safety and tolerability of QTX3046 as a single agent or in combination with cetuximab.

Conditions Studied

Interventions

  • COMBINATION_PRODUCT Cetuximab
  • DRUG QTX3046

Study Locations (5)

Texas

  • The University of Texas MD Anderson Cancer Center - Houston
  • South Texas Accelerated Research Therapeutics, LLC San Antonio - San Antonio

Michigan

  • South Texas Accelerated Research Therapeutics, LLC Midwest - Grand Rapids

North Carolina

  • Duke Cancer Center - Durham

Utah

  • Huntsman Cancer Institute, University of Utah - Salt Lake City

Trial Details

FieldValue
Enrollment Target 240 participants
Start Date 2024-05-30
Est. Completion 2027-07-01
Phase Phase 1

Sponsor

Quanta Therapeutics

3 total trials

What the Registry Record Tells You About NCT06428500

The ClinicalTrials.gov registry entry for NCT06428500 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 192-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (25% higher). The listed sponsor is Quanta Therapeutics, which has 3 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Tumor appearing as the primary indexed condition, and to 2 interventions - of which Cetuximab is the first listed.

NCT06428500 reports 5 study locations spanning 4 distinct geographic areas - top geographies include Texas, Michigan, North Carolina.

Frequently Asked Questions

What is clinical trial NCT06428500 about?

NCT06428500 is a clinical study titled "QTX3046 in Patients With KRAS G12D Mutations". Phase 1 study to determine the safety and tolerability of QTX3046 as a single agent or in combination with cetuximab.

What is the current status of trial NCT06428500?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 240 participants. The study started on 2024-05-30. Estimated completion is 2027-07-01.

What conditions does trial NCT06428500 study?

This clinical trial studies the following conditions: Advanced Solid Tumor.

What interventions are being tested in trial NCT06428500?

The interventions under investigation include: Cetuximab (COMBINATION_PRODUCT), QTX3046 (DRUG).

Who is sponsoring clinical trial NCT06428500?

This trial is sponsored by Quanta Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06428500 being conducted?

This trial has 5 study locations across Michigan, North Carolina, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.