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NCT06401577 · ClinicalTrials.gov registry record

Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

A clinical trial of Acute Pancreatitis, sponsored by Milton S. Hershey Medical Center.

Recruiting
Registry status
800
Enrollment target
13
Study locations

NCT06401577: Recruiting study of Acute Pancreatitis, sponsored by Milton S. Hershey Medical Center.

NCT06401577 is a study of Acute Pancreatitis that is actively recruiting participants, run by Milton S. Hershey Medical Center. The registered enrollment target is 800 participants, below the 2,239-participant average among 10 other Acute Pancreatitis trials with a reported enrollment target (64% lower). The trial reports 13 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06401577, a study of Acute Pancreatitis, is actively recruiting participants, sponsored by Milton S. Hershey Medical Center.

RECRUITING
Registry status
800 participants
Enrollment target
13
Study locations

Study Summary

The DREAM-ON study will investigate whether continuous glucose monitoring (CGM) is useful to predict risk for developing diabetes mellitus (DM) and pre-diabetes mellitus (PDM), the need for insulin therapy among those who develop DM, and to determine whether CGM can provide insight into the pathophysiology and DM subtype among participants who have experienced an episode of acute pancreatitis (AP). Thus, the results of the DREAM-ON study could inform future clinical practice guidelines for the management AP as well as potentially extending the licensing authorization for CGM to include use in patients with pancreatogenic (Type 3c) DM.

Primary Outcome

time to onset of pre-diabetes mellitus during the 36-month longitudinal follow-up period

Conditions Studied

Interventions

  • DEVICE Dexcom Continuous Glucose Monitor (CGM)

Study Locations (13)

California

  • University of Southern California - Los Angeles
  • Cedars-Sinai Medical Center - Los Angeles
  • Stanford University - Stanford

Florida

  • University of Florida - Gainesville
  • AdventHealth - Orlando

Illinois

  • Northwestern University - Chicago
  • University of Illinois at Chicago - Chicago

Indiana

  • Indiana University - Indianapolis

Maryland

  • Johns Hopkins University - Baltimore

Minnesota

  • University of Minnesota - Minneapolis

Ohio

  • Ohio State University - Columbus

Pennsylvania

  • University of Pittsburgh - Pittsburgh

Trial Details

FieldValue
Enrollment Target 800 participants
Start Date 2024-10-16
Est. Completion 2027-03-31
Milton S. Hershey Medical Center

396 total trials

What NCT06401577 shows while recruiting

NCT06401577 is an observational study that tracks outcomes without assigning an intervention. The registered 800 participants enrollment target is mid-sized for trials with a published cap, below the 2,239-participant average among 10 other Acute Pancreatitis trials with a reported enrollment target (64% lower).

The record links to 1 condition, with Acute Pancreatitis appearing as the primary indexed condition, and to 1 intervention - of which Dexcom Continuous Glucose Monitor (CGM) is the first listed.

NCT06401577 lists 13 locations in 9 states (California, Florida, Illinois).

Frequently Asked Questions

What is clinical trial NCT06401577 about?

NCT06401577 is a clinical study titled "Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics". The DREAM-ON study will investigate whether continuous glucose monitoring (CGM) is useful to predict risk for developing diabetes mellitus (DM) and pre-diabetes mellitus (PDM), the need for insulin therapy among those who develop DM, and to determine whether CGM can provide insight into the pathophy...

What is the current status of trial NCT06401577?

This trial is currently recruiting. The enrollment target is 800 participants. The study started on 2024-10-16. Estimated completion is 2027-03-31.

What conditions does trial NCT06401577 study?

This clinical trial studies the following conditions: Acute Pancreatitis.

What interventions are being tested in trial NCT06401577?

The interventions under investigation include: Dexcom Continuous Glucose Monitor (CGM) (DEVICE).

Who is sponsoring clinical trial NCT06401577?

This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06401577 being conducted?

This trial has 13 study locations across California, Florida, Illinois, Indiana, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Acute Pancreatitis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06401577's enrollment target sits among peer trials

800 3rd of 10 higher than 7 of 10 other Acute Pancreatitis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Acute Pancreatitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06401577, the US trial registry maintained by the National Library of Medicine. NCT06401577 (mid enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.