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NCT06388707 · ClinicalTrials.gov registry record · Phase 1

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

A Phase 1 study of Epilepsy and Drug Resistant Epilepsy, sponsored by NaviFUS Corporation.

Recruiting
Registry status
Phase 1
Development phase
8
Enrollment target
3
Study locations

NCT06388707 is a Phase 1 study of Epilepsy and Drug Resistant Epilepsy that is actively recruiting participants, run by NaviFUS Corporation. The registered enrollment target is 8 participants, below the 952-participant average among 160 other Epilepsy trials with a reported enrollment target (99% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT06388707, a Phase 1 study of Epilepsy and Drug Resistant Epilepsy, is actively recruiting participants, sponsored by NaviFUS Corporation.

RECRUITING
Registry status
Phase 1
Development phase
8 participants
Enrollment target
3
Study locations

Study Summary

This will be a prospective, open-label, single-arm, multi-center, pilot study to evaluate the safety, tolerability, and preliminary efficacy of low-intensity focused ultrasound (LIFU) neuromodulation using NaviFUS System in patients with drug-resistant unilateral or bilateral temporal lobe epilepsy (DR-TLE).

Interventions

  • DEVICE NaviFUS System

Study Locations (3)

California

  • Stanford University School of Medicine - Palo Alto

Massachusetts

  • Brigham and Women's Hospital - Boston

Virginia

  • University of Virginia School of Medicine - Charlottesville

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2024-09-13
Est. Completion 2025-12-31
Phase Phase 1

Sponsor

NaviFUS Corporation

2 total trials

What the Registry Record Tells You About NCT06388707

The ClinicalTrials.gov registry entry for NCT06388707 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 952-participant average among 160 other Epilepsy trials with a reported enrollment target (99% lower). The listed sponsor is NaviFUS Corporation, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Epilepsy appearing as the primary indexed condition, and to 1 intervention - of which NaviFUS System is the first listed.

NCT06388707 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Massachusetts, Virginia.

Frequently Asked Questions

What is clinical trial NCT06388707 about?

NCT06388707 is a clinical study titled "A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy". This will be a prospective, open-label, single-arm, multi-center, pilot study to evaluate the safety, tolerability, and preliminary efficacy of low-intensity focused ultrasound (LIFU) neuromodulation using NaviFUS System in patients with drug-resistant unilateral or bilateral temporal lobe epilepsy ...

What is the current status of trial NCT06388707?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2024-09-13. Estimated completion is 2025-12-31.

What conditions does trial NCT06388707 study?

This clinical trial studies the following conditions: Epilepsy, Drug Resistant Epilepsy.

What interventions are being tested in trial NCT06388707?

The interventions under investigation include: NaviFUS System (DEVICE).

Who is sponsoring clinical trial NCT06388707?

This trial is sponsored by NaviFUS Corporation, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06388707 being conducted?

This trial has 3 study locations across California, Massachusetts, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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