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NCT06315283 · ClinicalTrials.gov registry record · Phase 1

An Open-Label Trial to Assess the Comparative Bioavailability of TV-44749 to Oral Olanzapine in Participants With Schizophrenia

A Phase 1 study, sponsored by Teva Branded Pharmaceutical Products R&D.

Completed
Registry status
Phase 1
Development phase
153
Enrollment target

NCT06315283 is a Phase 1 study that has completed, run by Teva Branded Pharmaceutical Products R&D. The registered enrollment target is 153 participants.

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The verdict

NCT06315283, a Phase 1 study, has completed, sponsored by Teva Branded Pharmaceutical Products R&D.

COMPLETED
Registry status
Phase 1
Development phase
153 participants
Enrollment target

Study Summary

The primary objective of the study is to evaluate the comparative bioavailability of TV-44749 administered subcutaneous (sc) to oral olanzapine (ZYPREXA®) at steady state in participants with schizophrenia. A secondary objective of this trial is to evaluate the safety and tolerability of multiple doses of TV-44749 administered sc in participants with schizophrenia. Another secondary objective of this trial is to compare additional pharmacokinetic parameters of TV-44749 administered sc with oral olanzapine (ZYPREXA®) at steady state in participants with schizophrenia. The total duration of participation in the trial for each participant is planned to be approximately 21 weeks.

Interventions

  • DRUG TV-44749
  • DRUG Oral olanzapine

Trial Details

FieldValue
Enrollment Target 153 participants
Start Date 2024-03-20
Est. Completion 2025-09-04
Phase Phase 1

What the Registry Record Tells You About NCT06315283

The ClinicalTrials.gov registry entry for NCT06315283 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 153 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Teva Branded Pharmaceutical Products R&D, which has 167 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which TV-44749 is the first listed.

NCT06315283 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06315283 about?

NCT06315283 is a clinical study titled "An Open-Label Trial to Assess the Comparative Bioavailability of TV-44749 to Oral Olanzapine in Participants With Schizophrenia". The primary objective of the study is to evaluate the comparative bioavailability of TV-44749 administered subcutaneous (sc) to oral olanzapine (ZYPREXA®) at steady state in participants with schizophrenia. A secondary objective of this trial is to evaluate the safety and tolerability of multiple d...

What is the current status of trial NCT06315283?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 153 participants. The study started on 2024-03-20. Estimated completion is 2025-09-04.

What interventions are being tested in trial NCT06315283?

The interventions under investigation include: TV-44749 (DRUG), Oral olanzapine (DRUG).

Who is sponsoring clinical trial NCT06315283?

This trial is sponsored by Teva Branded Pharmaceutical Products R&D, which has 167 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.