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NCT06297278 · ClinicalTrials.gov registry record · NA
Exercise Facilitation of Adolescent Fear Extinction, Frontolimbic Circuitry, and Endocannabinoids
A NA study of Adolescence, sponsored by Wayne State University.
- Recruiting
- Registry status
- NA
- Development phase
- 174
- Enrollment target
- 1
- Study location
NCT06297278: Recruiting NA study of Adolescence, sponsored by Wayne State University.
NCT06297278 is a NA study of Adolescence that is actively recruiting participants, run by Wayne State University. The registered enrollment target is 174 participants, above the 86-participant average among 3 other Adolescence trials with a reported enrollment target (102% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06297278, a NA study of Adolescence, is actively recruiting participants, sponsored by Wayne State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 174 participants
- Enrollment target
- 1
- Study location
Study Summary
Anxiety disorders commonly begin during adolescence, and are characterized by deficits in the ability to inhibit or extinguish pathological fear. Recent research has provided new understanding of how fear is learned and can be regulated in the adolescent brain, and how the endocannabinoid system shapes these processes; however, these advances have not yet translated into improved therapeutic outcomes for adolescents with anxiety. This study will test whether a behavioral intervention, acute exercise, can help to improve fear regulation by enhancing brain activity and endocannabinoid signaling. This line of research may ultimately lead to more effect treatments for adolescent anxiety, and to new preventive strategies for at-risk youth.
Primary Outcome
To compare the effects of acute moderate-intensity exercise (vs. sedentary control) on extinction recall, the investigators will place three electrodes on participant's left hand to acquire SCR data using a BIOPAC MP160 Data Acquisition System (BIOPAC Systems, Inc.).
Conditions Studied
Interventions
- BEHAVIORAL Moderate Intensity Exercise
Study Locations (1)
Michigan
- Tolan Park Medical Building - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 174 participants |
| Start Date | 2024-05-17 |
| Est. Completion | 2028-04-30 |
| Phase | NA |
What NCT06297278 shows while recruiting
NCT06297278 is an interventional study that assigns participants to a tested intervention. The registered 174 participants enrollment target is mid-sized for trials with a published cap, above the 86-participant average among 3 other Adolescence trials with a reported enrollment target (102% higher).
The record links to 1 condition, with Adolescence appearing as the primary indexed condition, and to 1 intervention - of which Moderate Intensity Exercise is the first listed.
NCT06297278 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT06297278 about?
NCT06297278 is a clinical study titled "Exercise Facilitation of Adolescent Fear Extinction, Frontolimbic Circuitry, and Endocannabinoids". Anxiety disorders commonly begin during adolescence, and are characterized by deficits in the ability to inhibit or extinguish pathological fear. Recent research has provided new understanding of how fear is learned and can be regulated in the adolescent brain, and how the endocannabinoid system sha...
What is the current status of trial NCT06297278?
This trial is currently recruiting. It is a NA study. The enrollment target is 174 participants. The study started on 2024-05-17. Estimated completion is 2028-04-30.
What conditions does trial NCT06297278 study?
This clinical trial studies the following conditions: Adolescence.
What interventions are being tested in trial NCT06297278?
The interventions under investigation include: Moderate Intensity Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT06297278?
This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06297278 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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