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NCT06288256 · ClinicalTrials.gov registry record
Neurocognitive and Genomic Predictors of Persistent Pain and Opioid Misuse After Spine Surgery
A clinical trial of Lumbar Spine Pathology and Elective Spine Surgery, sponsored by Icahn School of Medicine at Mount Sinai.
- Recruiting
- Registry status
- 60
- Enrollment target
- 1
- Study location
NCT06288256 is a study of Lumbar Spine Pathology and Elective Spine Surgery that is actively recruiting participants, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 60 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06288256, a study of Lumbar Spine Pathology and Elective Spine Surgery, is actively recruiting participants, sponsored by Icahn School of Medicine at Mount Sinai.
- RECRUITING
- Registry status
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Having spine surgery and recovery is a vulnerable period when opioid naive patients may transition into long-term use of opioids, and when previously opioid tolerant patients may be at risk to continue towards long-term opioid use and dependence. However, little is known about risk for developing opioid misuse, taking opioids differently than indicated or prescribed, and later OUD. This study addresses the question of whether behavior, cognitive features, and genomic markers can predict misuse of opioids, persistent pain and disability in individuals after spine surgery. To determine if impulsivity, inhibitory control, drug choice, and/or cognitive distortions predict opioid misuse and disability in spine surgery patients with differential gene expression. This is a prospective observational longitudinal study characterizing behavioral phenotypes in adults undergoing spine surgery using both patient-reported survey measures, cognitive testing and blood sampling. Outcome measures include correlations between impulsivity measures, opioid drug choice responses and cognitive distortion scores, and opioid misuse with spine related disability, and gene expression counts.
Conditions Studied
Interventions
- OTHER No Intervention
Study Locations (1)
New York
- Mount Sinai Spine Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-03-27 |
| Est. Completion | 2026-07 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06288256
The ClinicalTrials.gov registry entry for NCT06288256 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Icahn School of Medicine at Mount Sinai, which has 708 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Lumbar Spine Pathology appearing as the primary indexed condition, and to 1 intervention - of which No Intervention is the first listed.
NCT06288256 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT06288256 about?
NCT06288256 is a clinical study titled "Neurocognitive and Genomic Predictors of Persistent Pain and Opioid Misuse After Spine Surgery". Having spine surgery and recovery is a vulnerable period when opioid naive patients may transition into long-term use of opioids, and when previously opioid tolerant patients may be at risk to continue towards long-term opioid use and dependence. However, little is known about risk for developing op...
What is the current status of trial NCT06288256?
This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2023-03-27. Estimated completion is 2026-07.
What conditions does trial NCT06288256 study?
This clinical trial studies the following conditions: Lumbar Spine Pathology, Elective Spine Surgery.
What interventions are being tested in trial NCT06288256?
The interventions under investigation include: No Intervention (OTHER).
Who is sponsoring clinical trial NCT06288256?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06288256 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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