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NCT06281977 · ClinicalTrials.gov registry record · Phase 3
Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm
A Phase 3 study, sponsored by Ottawa Heart Institute Research Corporation.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 192
- Enrollment target
NCT06281977: Recruiting Phase 3 study, sponsored by Ottawa Heart Institute Research Corporation.
NCT06281977 is a Phase 3 study that is actively recruiting participants, run by Ottawa Heart Institute Research Corporation. The registered enrollment target is 192 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06281977, a Phase 3 study, is actively recruiting participants, sponsored by Ottawa Heart Institute Research Corporation.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 192 participants
- Enrollment target
Study Summary
The objective of this study is to determine if there is a meaningful benefit to using the sedative medication dexmedetomidine in the acute treatment of patients with recurrent ventricular arrhythmias, known as electrical storm. This will be a multi-centre, double-blinded, placebo-controlled, randomized trial. Patients with electrical storm will be randomized to receive 48 to 72 hours of dexmedetomidine or placebo as part of their initial treatment in an intensive care unit.
Primary Outcome
Defined as anytime after the participant starts receiving dexmedetomidine or normal saline placebo
Interventions
- DRUG Normal saline
- DRUG Dexmedetomidine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 192 participants |
| Start Date | 2024-05-08 |
| Est. Completion | 2027-08-01 |
| Phase | Phase 3 |
What NCT06281977 shows while recruiting
NCT06281977 is an interventional study that assigns participants to a tested intervention. The registered 192 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 2 interventions - of which Normal saline is the first listed.
NCT06281977 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06281977 about?
NCT06281977 is a clinical study titled "Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm". The objective of this study is to determine if there is a meaningful benefit to using the sedative medication dexmedetomidine in the acute treatment of patients with recurrent ventricular arrhythmias, known as electrical storm. This will be a multi-centre, double-blinded, placebo-controlled, randomi...
What is the current status of trial NCT06281977?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 192 participants. The study started on 2024-05-08. Estimated completion is 2027-08-01.
What interventions are being tested in trial NCT06281977?
The interventions under investigation include: Normal saline (DRUG), Dexmedetomidine (DRUG).
Who is sponsoring clinical trial NCT06281977?
This trial is sponsored by Ottawa Heart Institute Research Corporation, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06281977's enrollment target sits among peer trials
192 1398th of 2000 higher than 599 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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