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NCT06273163 · ClinicalTrials.gov registry record · NA

Identifying Strategies to Curtail Weight Regain After GLP-1 Receptor Agonist Treatment Cessation

A NA study, sponsored by University of Texas Southwestern Medical Center.

Terminated
Registry status
NA
Development phase
39
Enrollment target

NCT06273163 is a NA study that was terminated before completion, run by University of Texas Southwestern Medical Center. The registered enrollment target is 39 participants.

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The verdict

NCT06273163, a NA study, was terminated before completion, sponsored by University of Texas Southwestern Medical Center.

TERMINATED
Registry status
NA
Development phase
39 participants
Enrollment target

Study Summary

Longitudinal studies show there is a steep increase in weight regain in the first 3-4 months after stopping GLP-1 receptor agonist medications (GLP-1s) and most patients regain most of their weight within a year. Insurers now question the utility of GLP-1s for weight loss as they are hesitant to cover these costs long-term (\~$833 per person per month). Some patients would also prefer not to take these medications in perpetuity and are likely to struggle with lifelong adherence. These challenges present an opportunity to test alternative interventions, such as meal replacements and behavioral treatments, to support weight maintenance after successful weight loss with GLP-1s. This regimen would allow patients to benefit from significant weight loss in the first year of taking GLP-1s and use more cost effective and sustainable strategies for long-term maintenance.

Interventions

  • OTHER Usual care
  • OTHER Medically tailored meals
  • BEHAVIORAL Noom®

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2024-03-05
Est. Completion 2025-08-05
Phase NA

What the Registry Record Tells You About NCT06273163

The ClinicalTrials.gov registry entry for NCT06273163 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 39 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Usual care is the first listed.

NCT06273163 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06273163 about?

NCT06273163 is a clinical study titled "Identifying Strategies to Curtail Weight Regain After GLP-1 Receptor Agonist Treatment Cessation". Longitudinal studies show there is a steep increase in weight regain in the first 3-4 months after stopping GLP-1 receptor agonist medications (GLP-1s) and most patients regain most of their weight within a year. Insurers now question the utility of GLP-1s for weight loss as they are hesitant to cov...

What is the current status of trial NCT06273163?

This trial is currently terminated. It is a NA study. The enrollment target is 39 participants. The study started on 2024-03-05. Estimated completion is 2025-08-05.

What interventions are being tested in trial NCT06273163?

The interventions under investigation include: Usual care (OTHER), Medically tailored meals (OTHER), Noom® (BEHAVIORAL).

Who is sponsoring clinical trial NCT06273163?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.