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NCT06270251 · ClinicalTrials.gov registry record · NA

Modeling Tic Change During Behavior Therapy for Tics

A NA study of Chronic Tic Disorder, sponsored by University of Minnesota.

Recruiting
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT06270251 is a NA study of Chronic Tic Disorder that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 30 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT06270251, a NA study of Chronic Tic Disorder, is actively recruiting participants, sponsored by University of Minnesota.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

Chronic tics are a disabling neuropsychiatric symptom associated with multiple child-onset mental disorders. Chronic tics affect 1-3% of youth and can be associated with impaired functioning, emotional and behavioral problems, physical pain, diminished quality of life, and peer victimization. Chronic tics are the primary symptom of Tourette Syndrome (TS) and Persistent Motor/Vocal Tic Disorders. CBIT is a manualized treatment focused on increasing tic controllability. Its core procedure is competing response training (CRT), in which patients learn to inhibit tics by learning and applying a competing motor action to one tic at a time. CBIT is recommended as a first-line treatment relative to medications and other therapies. However, only 52% of children and 38% of adults show clinically meaningful tic improvement. Large randomized trials have demonstrated the superiority of CBIT over supportive therapy in child and adult patients, and meta-analysis shows comparable effect sizes for CBIT and medication. Although increasing tic controllability is the primary goal of CBIT, tic controllability nor its correlates have been examined longitudinally during the intervention. The overall objective of this study is to use fine-grained data collection strategies to identify patterns in tic controllability and other relevant related variables that are associated with treatment response to CBIT. Participants with chronic tics will complete a manualized course of 8-session CBIT. Behavioral, psychosocial, and global functioning will be assessed longitudinally to examine predictors and correlates of response. CBIT sessions will be video recorded.

Conditions Studied

Interventions

  • BEHAVIORAL CBIT

Study Locations (1)

Minnesota

  • University of Minnesota - Minneapolis

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2024-03-01
Est. Completion 2028-09-01
Phase NA

Sponsor

University of Minnesota

966 total trials

What the Registry Record Tells You About NCT06270251

The ClinicalTrials.gov registry entry for NCT06270251 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Chronic Tic Disorder appearing as the primary indexed condition, and to 1 intervention - of which CBIT is the first listed.

NCT06270251 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT06270251 about?

NCT06270251 is a clinical study titled "Modeling Tic Change During Behavior Therapy for Tics". Chronic tics are a disabling neuropsychiatric symptom associated with multiple child-onset mental disorders. Chronic tics affect 1-3% of youth and can be associated with impaired functioning, emotional and behavioral problems, physical pain, diminished quality of life, and peer victimization. Chroni...

What is the current status of trial NCT06270251?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2024-03-01. Estimated completion is 2028-09-01.

What conditions does trial NCT06270251 study?

This clinical trial studies the following conditions: Chronic Tic Disorder.

What interventions are being tested in trial NCT06270251?

The interventions under investigation include: CBIT (BEHAVIORAL).

Who is sponsoring clinical trial NCT06270251?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06270251 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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