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NCT06261840 · ClinicalTrials.gov registry record · Phase 4

Refining Treatment Options for Trichomonas Vaginalis Infection: A Comparative Analysis of Metronidazole and Secnidazole

A Phase 4 study of Trichomonas Vaginitis and Bacterial Vaginitis, sponsored by Tulane University.

Recruiting
Registry status
Phase 4
Development phase
1,200
Enrollment target
4
Study locations

NCT06261840: Recruiting Phase 4 study of Trichomonas Vaginitis and Bacterial Vaginitis, sponsored by Tulane University.

NCT06261840 is a Phase 4 study of Trichomonas Vaginitis and Bacterial Vaginitis that is actively recruiting participants, run by Tulane University. The registered enrollment target is 1,200 participants, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (132% higher). The trial reports 4 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06261840, a Phase 4 study of Trichomonas Vaginitis and Bacterial Vaginitis, is actively recruiting participants, sponsored by Tulane University.

RECRUITING
Registry status
Phase 4
Development phase
1,200 participants
Enrollment target
4
Study locations

Study Summary

This is a multi-centered, randomized, open-label, parallel, phase IV clinical trial comparing the effectiveness and cost-effectiveness of oral multi-dose metronidazole (MTZ) and oral single-dose secnidazole (SEC) for the treatment of Trichomonas vaginalis in both women and men.

Primary Outcome

A repeat T. vaginalis NAAT test will be completed at the test of cure (TOC) visit

Interventions

  • DRUG Metronidazole 500 mg
  • DRUG Secnidazole 2000 MG

Study Locations (4)

Alabama

  • University of Alabama at Birmingham [UAB] Gynecology Clinics - Birmingham
  • UAB Sexual Health Research Clinic [SHRC] - Birmingham

Florida

  • Segal Trials Healthcare Clinical Data, Inc. 1065 NE 125th St. Suite 417 North Miami, FL 33161 - North Miami

Louisiana

  • LSU-CrescentCare Sexual Health Center - New Orleans

Trial Details

FieldValue
Enrollment Target 1,200 participants
Start Date 2025-05-06
Est. Completion 2029-07-31
Phase Phase 4
Tulane University

73 total trials

What NCT06261840 shows while recruiting

NCT06261840 is an interventional study that assigns participants to a tested intervention. Its 1,200 participants enrollment target places it among the larger protocols in the corpus, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (132% higher).

The record links to 2 conditions, with Trichomonas Vaginitis appearing as the primary indexed condition, and to 2 interventions - of which Metronidazole 500 mg is the first listed.

NCT06261840 reports a single indexed study location in Alabama, Florida, Louisiana.

Frequently Asked Questions

What is clinical trial NCT06261840 about?

NCT06261840 is a clinical study titled "Refining Treatment Options for Trichomonas Vaginalis Infection: A Comparative Analysis of Metronidazole and Secnidazole". This is a multi-centered, randomized, open-label, parallel, phase IV clinical trial comparing the effectiveness and cost-effectiveness of oral multi-dose metronidazole (MTZ) and oral single-dose secnidazole (SEC) for the treatment of Trichomonas vaginalis in both women and men.

What is the current status of trial NCT06261840?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 1,200 participants. The study started on 2025-05-06. Estimated completion is 2029-07-31.

What conditions does trial NCT06261840 study?

This clinical trial studies the following conditions: Trichomonas Vaginitis, Bacterial Vaginitis.

What interventions are being tested in trial NCT06261840?

The interventions under investigation include: Metronidazole 500 mg (DRUG), Secnidazole 2000 MG (DRUG).

Who is sponsoring clinical trial NCT06261840?

This trial is sponsored by Tulane University, which has 73 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06261840 being conducted?

This trial has 4 study locations across Alabama, Florida, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Trichomonas Vaginitis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06261840's enrollment target sits among peer trials

1,200 62nd of 2000 higher than 1,939 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06261840, the US trial registry maintained by the National Library of Medicine. NCT06261840 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.