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NCT06242678 · ClinicalTrials.gov registry record · NA
Evaluating Spinal Cord Stimulation for Stiff Person Syndrome
A NA study, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- NA
- Development phase
- 2
- Enrollment target
NCT06242678: Completed NA study, sponsored by Wake Forest University Health Sciences.
NCT06242678 is a NA study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06242678, a NA study, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- NA
- Development phase
- 2 participants
- Enrollment target
Study Summary
The purpose of this prospective pilot study is to gather preliminary evidence evaluating spinal cord stimulation (SCS) as a potential therapy for the treatment of rigidity and painful spasms in patients with stiff person syndrome (SPS), a rare autoimmune neurological condition. The hypothesis is that SCS-mediated clinical improvement occurs through multi-modal mechanisms of action targeting several components of neuronal inhibitory signaling pathways in the spinal cord.
Primary Outcome
baseline pain will be measured on a 0-100 scale, with 100 being the worse level of pain, with improvement in pain level measured immediately prior to removal (kept in up to 10 days), with pain level reassessed at 14 days after trial leads removed to see if returned to baseline
Interventions
- DEVICE SCS trial lead
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2024-11-01 |
| Est. Completion | 2025-10-27 |
| Phase | NA |
What the finished NCT06242678 record still lists
NCT06242678 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which SCS trial lead is the first listed.
NCT06242678 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06242678 about?
NCT06242678 is a clinical study titled "Evaluating Spinal Cord Stimulation for Stiff Person Syndrome". The purpose of this prospective pilot study is to gather preliminary evidence evaluating spinal cord stimulation (SCS) as a potential therapy for the treatment of rigidity and painful spasms in patients with stiff person syndrome (SPS), a rare autoimmune neurological condition. The hypothesis is tha...
What is the current status of trial NCT06242678?
This trial is currently completed. It is a NA study. The enrollment target is 2 participants. The study started on 2024-11-01. Estimated completion is 2025-10-27.
What interventions are being tested in trial NCT06242678?
The interventions under investigation include: SCS trial lead (DEVICE).
Who is sponsoring clinical trial NCT06242678?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06242678's enrollment target sits among peer trials
2 1997th of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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