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NCT06226610 · ClinicalTrials.gov registry record · Phase 2

Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory Clinic

A Phase 2 study of Pruritis, sponsored by Akron Children's Hospital.

Recruiting
Registry status
Phase 2
Development phase
46
Enrollment target
1
Study location

NCT06226610: Recruiting Phase 2 study of Pruritis, sponsored by Akron Children's Hospital.

NCT06226610 is a Phase 2 study of Pruritis that is actively recruiting participants, run by Akron Children's Hospital. The registered enrollment target is 46 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (65% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06226610, a Phase 2 study of Pruritis, is actively recruiting participants, sponsored by Akron Children's Hospital.

RECRUITING
Registry status
Phase 2
Development phase
46 participants
Enrollment target
1
Study location

Study Summary

The goal of this study is to test the efficacy of Dupixent in improving post-burn itching symptoms versus the current standard of care.

Primary Outcome

Participants' Itch Severity Scale (ISS) scores will decrease more than 2.0 points after 12 weeks following initiating use of Dupixent

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG Dupilumab

Study Locations (1)

Ohio

  • Akron Children's Hospital - Akron

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 2024-11-21
Est. Completion 2026-12-31
Phase Phase 2
Akron Children's Hospital

27 total trials

What NCT06226610 shows while recruiting

NCT06226610 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (65% lower).

The record links to 1 condition, with Pruritis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06226610 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT06226610 about?

NCT06226610 is a clinical study titled "Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory Clinic". The goal of this study is to test the efficacy of Dupixent in improving post-burn itching symptoms versus the current standard of care.

What is the current status of trial NCT06226610?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 46 participants. The study started on 2024-11-21. Estimated completion is 2026-12-31.

What conditions does trial NCT06226610 study?

This clinical trial studies the following conditions: Pruritis.

What interventions are being tested in trial NCT06226610?

The interventions under investigation include: Placebo (OTHER), Dupilumab (DRUG).

Who is sponsoring clinical trial NCT06226610?

This trial is sponsored by Akron Children's Hospital, which has 27 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06226610 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pruritis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06226610's enrollment target sits among peer trials

46 1286th of 2000 higher than 706 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06226610, the US trial registry maintained by the National Library of Medicine. NCT06226610 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.