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NCT06216704 · ClinicalTrials.gov registry record
Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis
A clinical trial of Cystic Fibrosis, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- 36
- Enrollment target
- 1
- Study location
NCT06216704: Recruiting study of Cystic Fibrosis, sponsored by Massachusetts General Hospital.
NCT06216704 is a study of Cystic Fibrosis that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 36 participants, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06216704, a study of Cystic Fibrosis, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators will be evaluating bone marrow composition via magnetic resonance imaging in adolescents diagnosed with cystic fibrosis (CF) compared to healthy, matched controls. The investigators will also be assessing their bone mineral density via other imaging modalities, including dual-energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT). This longitudinal project will focus on abnormalities in bone marrow composition, and specifically whether adolescents with diagnosed with CF exhibit increased bone marrow fat, its association with bone mineral density (BMD) and the underlying pathophysiology, including glycemic control, inflammation, and bone turnover markers.
Primary Outcome
Change in bone marrow adiposity measured by MR relaxometry
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Blood Draw
- DIAGNOSTIC_TEST Magnetic resonance relaxometry
- DIAGNOSTIC_TEST Magnetic resonance spectroscopy
- DIAGNOSTIC_TEST DXA
- DIAGNOSTIC_TEST pQCT
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2024-04-01 |
| Est. Completion | 2029-06-30 |
What NCT06216704 shows while recruiting
NCT06216704 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Cystic Fibrosis appearing as the primary indexed condition, and to 5 interventions - of which Blood Draw is the first listed.
NCT06216704 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06216704 about?
NCT06216704 is a clinical study titled "Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis". The investigators will be evaluating bone marrow composition via magnetic resonance imaging in adolescents diagnosed with cystic fibrosis (CF) compared to healthy, matched controls. The investigators will also be assessing their bone mineral density via other imaging modalities, including dual-energ...
What is the current status of trial NCT06216704?
This trial is currently recruiting. The enrollment target is 36 participants. The study started on 2024-04-01. Estimated completion is 2029-06-30.
What conditions does trial NCT06216704 study?
This clinical trial studies the following conditions: Cystic Fibrosis.
What interventions are being tested in trial NCT06216704?
The interventions under investigation include: Blood Draw (DIAGNOSTIC_TEST), Magnetic resonance relaxometry (DIAGNOSTIC_TEST), Magnetic resonance spectroscopy (DIAGNOSTIC_TEST), DXA (DIAGNOSTIC_TEST), pQCT (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06216704?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06216704 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cystic Fibrosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06216704's enrollment target sits among peer trials
36 107th of 169 higher than 61 of 169 other Cystic Fibrosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cystic Fibrosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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