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NCT06185686 · ClinicalTrials.gov registry record
Radiation Induced Alterations in Resting State Brain Networks in Pediatric Brain Tumor Patients
A clinical trial of Brain Tumor, Primary, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- 16
- Enrollment target
- 1
- Study location
NCT06185686 is a study of Brain Tumor, Primary that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 16 participants, below the 322-participant average among 3 other Brain Tumor, Primary trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06185686, a study of Brain Tumor, Primary, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
With modern therapy, the survival rate for pediatric brain tumor patients has significantly improved, with over 70% of patients surviving their disease. However, this progress often comes at the cost of substantial morbidity, with cognitive deficits being the primary obstacle to independent living. Robust predictors of cognitive decline and a comprehensive understanding of the underlying mechanisms of cognitive injury remain elusive. This study will prospectively investigate alterations in brain resting state networks following radiation therapy using functional imaging. The hypothesis is that radiation therapy leads to dose-dependent alterations in functional connectivity in the networks associated with higher level cognition, ultimately leading to cognitive decline.
Conditions Studied
Interventions
- OTHER Cognitive testing
- DEVICE Resting State MRI/Precision functional mapping
Study Locations (1)
Missouri
- Washington University School of Medicine/Saint Louis Children's Hospital - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2024-07-10 |
| Est. Completion | 2027-07-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06185686
The ClinicalTrials.gov registry entry for NCT06185686 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 322-participant average among 3 other Brain Tumor, Primary trials with a reported enrollment target (95% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Brain Tumor, Primary appearing as the primary indexed condition, and to 2 interventions - of which Cognitive testing is the first listed.
NCT06185686 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.
Frequently Asked Questions
What is clinical trial NCT06185686 about?
NCT06185686 is a clinical study titled "Radiation Induced Alterations in Resting State Brain Networks in Pediatric Brain Tumor Patients". With modern therapy, the survival rate for pediatric brain tumor patients has significantly improved, with over 70% of patients surviving their disease. However, this progress often comes at the cost of substantial morbidity, with cognitive deficits being the primary obstacle to independent living. ...
What is the current status of trial NCT06185686?
This trial is currently recruiting. The enrollment target is 16 participants. The study started on 2024-07-10. Estimated completion is 2027-07-31.
What conditions does trial NCT06185686 study?
This clinical trial studies the following conditions: Brain Tumor, Primary.
What interventions are being tested in trial NCT06185686?
The interventions under investigation include: Cognitive testing (OTHER), Resting State MRI/Precision functional mapping (DEVICE).
Who is sponsoring clinical trial NCT06185686?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06185686 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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