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NCT06173128 · ClinicalTrials.gov registry record
Respiratory Microbiota and Immune Response in CVID
A clinical trial of CVID, sponsored by Boston University.
- Completed
- Registry status
- 75
- Enrollment target
- 1
- Study location
NCT06173128: Completed study of CVID, sponsored by Boston University.
NCT06173128 is a study of CVID that has completed, run by Boston University. The registered enrollment target is 75 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06173128, a study of CVID, has completed, sponsored by Boston University.
- COMPLETED
- Registry status
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency. Respiratory ailments are the most frequent complications of CVID, with chronic pulmonary disease developing in 30-60% and even more experiencing frequent acute respiratory infections. This project aims to establish cutting-edge approaches to study pulmonary biology in CVID and apply novel bioinformatics strategies to study complex interactions among microbes and host cells by direct sampling of the respiratory tract. The central hypothesis for this research is that antibody (Ab) deficiency in CVID alters respiratory microbiota and host interactions to drive pulmonary disease.
Primary Outcome
Quality control analysis of RNA samples collected from nasopharyngeal swabs for adequacy to perform RNA-seq analysis will be performed. This will be done using the Boston University (BU) Medical Campus RNA core facility bioanalyzer, which will assess for adequate RNA quality and quantity for RNA-seq
Conditions Studied
Study Locations (1)
Massachusetts
- Boston Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2024-03-15 |
| Est. Completion | 2026-02-15 |
What the finished NCT06173128 record still lists
NCT06173128 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 75 participants, a relatively small participant target.
The record links to 1 condition, with CVID appearing as the primary indexed condition, and to 0 interventions.
NCT06173128 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06173128 about?
NCT06173128 is a clinical study titled "Respiratory Microbiota and Immune Response in CVID". Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency. Respiratory ailments are the most frequent complications of CVID, with chronic pulmonary disease developing in 30-60% and even more experiencing frequent acute respiratory infections. This project aim...
What is the current status of trial NCT06173128?
This trial is currently completed. The enrollment target is 75 participants. The study started on 2024-03-15. Estimated completion is 2026-02-15.
What conditions does trial NCT06173128 study?
This clinical trial studies the following conditions: CVID.
Who is sponsoring clinical trial NCT06173128?
This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06173128 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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