Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
NCT06143878 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of the study is to see how effective JNJ-77242113 is in participants with moderate to severe plaque psoriasis compared to placebo and deucravacitinib.
Conditions Studied
Interventions
- DRUG Deucravacitinib
- DRUG JNJ-77242113
- DRUG JNJ-77242113 Matching Placebo
- DRUG Deucravacitinib Matching Placebo
Study Locations (20)
California
- First OC Dermatology — Fountain Valley
- Center for Dermatology Clinical Research — Fremont
- Integrative Skin Science and Research — Sacramento
- Southern California Dermatology — Santa Ana
- Clinical Science Institute — Santa Monica
Florida
- Driven Research LLC — Coral Gables
- Ziaderm Research LLC — North Miami Beach
- Renstar Medical Research — Ocala
- Forcare Clinical Research Inc — Tampa
Illinois
- DeNova Research — Chicago
- Arlington Dermatology — Rolling Meadows
- Northshore Medical Group — Skokie
- Dundee Dermatology — West Dundee
Arizona
- Medical Dermatology Specialists — Phoenix
- Center for Dermatology and Plastic Surgery — Scottsdale
Georgia
- Hamilton Research LLC — Alpharetta
- Skin Care Physicians of Georgia — Macon
Indiana
- Dawes Fretzin Clinical Research Group LLC — Indianapolis
- Indiana Clinical Trial Center — Plainfield
Arkansas
- Johnson Dermatology — Fort Smith
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 774 participants |
| Start Date | 2024-02-01 |
| Est. Completion | 2027-06-01 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06143878
The ClinicalTrials.gov registry entry for NCT06143878 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 774 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 442 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Plaque Psoriasis appearing as the primary indexed condition, and to 4 interventions — of which Deucravacitinib is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06143878 reports 20 study locations spanning 7 distinct geographic areas — top geographies include California, Florida, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06143878 about?
NCT06143878 is a clinical study titled "A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis". The purpose of the study is to see how effective JNJ-77242113 is in participants with moderate to severe plaque psoriasis compared to placebo and deucravacitinib.
What is the current status of trial NCT06143878?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 774 participants. The study started on 2024-02-01. Estimated completion is 2027-06-01.
What conditions does trial NCT06143878 study?
This clinical trial studies the following conditions: Plaque Psoriasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06143878?
The interventions under investigation include: Deucravacitinib (DRUG), JNJ-77242113 (DRUG), JNJ-77242113 Matching Placebo (DRUG), Deucravacitinib Matching Placebo (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06143878?
This trial is sponsored by Janssen Research & Development, which has 442 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06143878 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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