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NCT06140823 · ClinicalTrials.gov registry record
Prospective Validation of Liver Cancer Risk Computation (LIRIC) Models
A clinical trial of Predictive Cancer Model, sponsored by Beth Israel Deaconess Medical Center.
- Active
- Registry status
- 6,000,000
- Enrollment target
- 1
- Study location
NCT06140823 is a study of Predictive Cancer Model that is active but no longer recruiting, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 6,000,000 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06140823, a study of Predictive Cancer Model, is active but no longer recruiting, sponsored by Beth Israel Deaconess Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- 6,000,000 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this prospective observational cohort study is to validate previously developed Hepatocellular Carcinoma (HCC) risk prediction algorithms, the Liver Risk Computation (LIRIC) models, which are based on electronic health records. The main questions it aims to answer are: * Will our retrospectively developed general population LIRIC models, developed on routine EHR data, perform similarly when prospectively validated, and reliably and accurately predict HCC in real-time? * What is the average time from model deployment and risk prediction, to the date of HCC development and what is the stage of HCC at diagnosis? The risk model will be deployed on data from individuals eligible for the study. Each individual will be assigned a risk score and tracked over time to assess the model's discriminatory performance and calibration.
Conditions Studied
Interventions
- OTHER Liver Risk Computation Model (LIRIC)
- OTHER Liver Risk Computation Model (LIRIC)_cirrhosis
- OTHER Liver Risk Computation Model (LIRIC)_no_cirrhosis
Study Locations (1)
Massachusetts
- Beth Israel Deaconess Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6,000,000 participants |
| Start Date | 2023-04-01 |
| Est. Completion | 2027-03-31 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06140823
The ClinicalTrials.gov registry entry for NCT06140823 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 6,000,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Predictive Cancer Model appearing as the primary indexed condition, and to 3 interventions - of which Liver Risk Computation Model (LIRIC) is the first listed.
NCT06140823 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06140823 about?
NCT06140823 is a clinical study titled "Prospective Validation of Liver Cancer Risk Computation (LIRIC) Models". The goal of this prospective observational cohort study is to validate previously developed Hepatocellular Carcinoma (HCC) risk prediction algorithms, the Liver Risk Computation (LIRIC) models, which are based on electronic health records. The main questions it aims to answer are: * Will our retro...
What is the current status of trial NCT06140823?
This trial is currently active not recruiting. The enrollment target is 6,000,000 participants. The study started on 2023-04-01. Estimated completion is 2027-03-31.
What conditions does trial NCT06140823 study?
This clinical trial studies the following conditions: Predictive Cancer Model.
What interventions are being tested in trial NCT06140823?
The interventions under investigation include: Liver Risk Computation Model (LIRIC) (OTHER), Liver Risk Computation Model (LIRIC)_cirrhosis (OTHER), Liver Risk Computation Model (LIRIC)_no_cirrhosis (OTHER).
Who is sponsoring clinical trial NCT06140823?
This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06140823 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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