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NCT06136455 · ClinicalTrials.gov registry record · Phase 4
A Study to Investigate Salivary Flow and Potential of Hydrogen (pH) Following Use of Essential-Oil Containing Mouthwashes
A Phase 4 study, sponsored by Johnson & Johnson Consumer Inc. (J&JCI).
- Completed
- Registry status
- Phase 4
- Development phase
- 164
- Enrollment target
NCT06136455: Completed Phase 4 study, sponsored by Johnson & Johnson Consumer Inc. (J&JCI).
NCT06136455 is a Phase 4 study that has completed, run by Johnson & Johnson Consumer Inc. (J&JCI). The registered enrollment target is 164 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06136455, a Phase 4 study, has completed, sponsored by Johnson & Johnson Consumer Inc. (J&JCI).
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 164 participants
- Enrollment target
Study Summary
The purpose of this trial is to evaluate the amount of saliva generated and changes in the oral Potential of Hydrogen (pH) after a single use of essential oil (EO)-containing mouth rinses compared to a negative control. Three EO mouthwash formulations will be investigated in this regard, with the negative control being tap water.
Primary Outcome
Saliva samples will be collected by participants at specified timepoints. The final amount of saliva will be weighed and flow rate will be determined.
Interventions
- DRUG Colgate Cavity Protection Toothpaste
- DRUG Listerine Clinical Solutions Teeth Strength
- DRUG Listerine Total Care Zero Alcohol Mouthwash
- OTHER Listerine Cool Mint Zero Alcohol Mouthwash
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 164 participants |
| Start Date | 2023-11-13 |
| Est. Completion | 2023-11-16 |
| Phase | Phase 4 |
What the finished NCT06136455 record still lists
NCT06136455 is an interventional study that assigns participants to a tested intervention. The registered 164 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 4 interventions - of which Colgate Cavity Protection Toothpaste is the first listed.
NCT06136455 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06136455 about?
NCT06136455 is a clinical study titled "A Study to Investigate Salivary Flow and Potential of Hydrogen (pH) Following Use of Essential-Oil Containing Mouthwashes". The purpose of this trial is to evaluate the amount of saliva generated and changes in the oral Potential of Hydrogen (pH) after a single use of essential oil (EO)-containing mouth rinses compared to a negative control. Three EO mouthwash formulations will be investigated in this regard, with the ne...
What is the current status of trial NCT06136455?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 164 participants. The study started on 2023-11-13. Estimated completion is 2023-11-16.
What interventions are being tested in trial NCT06136455?
The interventions under investigation include: Colgate Cavity Protection Toothpaste (DRUG), Listerine Clinical Solutions Teeth Strength (DRUG), Listerine Total Care Zero Alcohol Mouthwash (DRUG), Listerine Cool Mint Zero Alcohol Mouthwash (OTHER).
Who is sponsoring clinical trial NCT06136455?
This trial is sponsored by Johnson & Johnson Consumer Inc. (J&JCI), which has 40 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06136455's enrollment target sits among peer trials
164 496th of 2000 higher than 1,500 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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