Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06132178 · ClinicalTrials.gov registry record · Phase 2
Psilocybin rTMS for Treatment Resistant Depression
A Phase 2 study of Depression and Major Depressive Disorder, sponsored by University of Texas at Austin.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06132178 is a Phase 2 study of Depression and Major Depressive Disorder that is actively recruiting participants, run by University of Texas at Austin. The registered enrollment target is 100 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06132178, a Phase 2 study of Depression and Major Depressive Disorder, is actively recruiting participants, sponsored by University of Texas at Austin.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine the safety and feasibility of sequencing psilocybin therapy with a short-duration, aiTBS protocol (Stanford Accelerated Intelligent Neuromodulation Therapy, or SAINT) in individuals with treatment-resistant major depressive disorder.
Conditions Studied
Interventions
- DRUG Psilocybin
- DEVICE Accelerated intermittent theta burst (aiTBS) rTMS treatment
- DRUG Low-dose psilocybin
- DEVICE Sham Accelerated intermittent theta burst (aiTBS) rTMS treatment
Study Locations (1)
Texas
- Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600 - Austin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-01-10 |
| Est. Completion | 2030-12-31 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06132178
The ClinicalTrials.gov registry entry for NCT06132178 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (87% lower). The listed sponsor is University of Texas at Austin, which has 257 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Depression appearing as the primary indexed condition, and to 4 interventions - of which Psilocybin is the first listed.
NCT06132178 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT06132178 about?
NCT06132178 is a clinical study titled "Psilocybin rTMS for Treatment Resistant Depression". The purpose of this study is to determine the safety and feasibility of sequencing psilocybin therapy with a short-duration, aiTBS protocol (Stanford Accelerated Intelligent Neuromodulation Therapy, or SAINT) in individuals with treatment-resistant major depressive disorder.
What is the current status of trial NCT06132178?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2025-01-10. Estimated completion is 2030-12-31.
What conditions does trial NCT06132178 study?
This clinical trial studies the following conditions: Depression, Major Depressive Disorder, Treatment-Resistant Depression, MDD, Recurrent Depression.
What interventions are being tested in trial NCT06132178?
The interventions under investigation include: Psilocybin (DRUG), Accelerated intermittent theta burst (aiTBS) rTMS treatment (DEVICE), Low-dose psilocybin (DRUG), Sham Accelerated intermittent theta burst (aiTBS) rTMS treatment (DEVICE).
Who is sponsoring clinical trial NCT06132178?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06132178 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Sleep to Reduce Incident Depression Effectively in Peripartum
RECRUITING · Phase 2
-
Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
RECRUITING · Phase 2
-
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
RECRUITING · Phase 2
-
Cannabidiol and Older Adult Cannabis Users
RECRUITING · Phase 2
-
Evaluation of a Keto-Like Supplement on Brain Responses to Emotional Stimuli in Depression
RECRUITING · Phase 2
-
Neurobiology of Suicide
RECRUITING · Phase 2
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.