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NCT06108336 · ClinicalTrials.gov registry record · NA
Cerebellar Involvement in Cognitive Sequencing
A NA study of Effects of Cerebellar Stimulation on Brain Activation, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06108336: Recruiting NA study of Effects of Cerebellar Stimulation on Brain Activation, sponsored by Johns Hopkins University.
NCT06108336 is a NA study of Effects of Cerebellar Stimulation on Brain Activation that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06108336, a NA study of Effects of Cerebellar Stimulation on Brain Activation, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Although there is increasing recognition that the cerebellum is involved in cognition as well as motor function, the manner in which the cerebellum contributes to cognition is uncertain. One theory that might account for both motor and cognitive contributions of the cerebellum is that the cerebellum is involved in sequencing of relevant events or stimuli. Previous experiments have suggested that disruption of the cerebellum impairs the prediction of the next event in a sequence. The present experiment will examine the impact of cerebellar stimulation on brain activation during the performance of both sequence-demanding and non-sequence-demanding tasks.
Primary Outcome
functional magnetic resonance imaging brain activation. For the sequential task, a sequence of letters is presented and the subject is presented with number signs, one at a time, to guide rehearsal of the sequence. At some point a probe letter is presented and the subject indicates by button press if the probe is the next letter in the sequence. For the non-sequential task, subjects do not have a guided rehearsal, and the response to the probe indicates if the probe was one of the letters origin
Conditions Studied
Interventions
- PROCEDURE TMS during sequence-demanding task
- PROCEDURE No TMS during sequence-demanding task
- PROCEDURE TMS during non-sequence-demanding task
- PROCEDURE No TMS during non-sequence-demanding task
Study Locations (1)
Maryland
- Johns Hopkins University School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-03-01 |
| Est. Completion | 2027-07-31 |
| Phase | NA |
What NCT06108336 shows while recruiting
NCT06108336 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Effects of Cerebellar Stimulation on Brain Activation appearing as the primary indexed condition, and to 4 interventions - of which TMS during sequence-demanding task is the first listed.
NCT06108336 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT06108336 about?
NCT06108336 is a clinical study titled "Cerebellar Involvement in Cognitive Sequencing". Although there is increasing recognition that the cerebellum is involved in cognition as well as motor function, the manner in which the cerebellum contributes to cognition is uncertain. One theory that might account for both motor and cognitive contributions of the cerebellum is that the cerebellum...
What is the current status of trial NCT06108336?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2024-03-01. Estimated completion is 2027-07-31.
What conditions does trial NCT06108336 study?
This clinical trial studies the following conditions: Effects of Cerebellar Stimulation on Brain Activation.
What interventions are being tested in trial NCT06108336?
The interventions under investigation include: TMS during sequence-demanding task (PROCEDURE), No TMS during sequence-demanding task (PROCEDURE), TMS during non-sequence-demanding task (PROCEDURE), No TMS during non-sequence-demanding task (PROCEDURE).
Who is sponsoring clinical trial NCT06108336?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06108336 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06108336's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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