Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 1

A Study of JNJ-87189401 Plus JNJ-78278343 for Advanced Prostate Cancer

NCT06095089 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of the study is to determine the recommended regimen for Phase 2 (RP2Rs) of combination of JNJ-87189401 with JNJ-78278343 (Part 1: dose escalation) and further evaluate the safety at RP2Rs (Part 2: dose expansion) in participants with advanced prostate cancer.

Conditions Studied

Interventions

  • DRUG JNJ-78278343
  • DRUG JNJ-87189401

Study Locations (6)

Other

  • Centre Leon Berard — Lyon
  • Institut Gustave Roussy — Villejuif

Colorado

  • University of Colorado Anschutz Medical Campus — Aurora

New York

  • Herbert Irving Comprehensive Cancer Center Columbia University Medical Center — New York

Tennessee

  • Tennessee Oncology — Nashville

Texas

  • South Texas Accelerated Research Therapeutics, LLC (START) — San Antonio

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2023-11-01
Est. Completion 2028-06-28
Phase Phase 1

Sponsor

Janssen Research & Development

442 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06095089

The ClinicalTrials.gov registry entry for NCT06095089 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 442 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Advanced Prostate Cancer appearing as the primary indexed condition, and to 2 interventions — of which JNJ-78278343 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06095089 reports 6 study locations spanning 5 distinct geographic areas — top geographies include Other, Colorado, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06095089 about?

NCT06095089 is a clinical study titled "A Study of JNJ-87189401 Plus JNJ-78278343 for Advanced Prostate Cancer". The purpose of the study is to determine the recommended regimen for Phase 2 (RP2Rs) of combination of JNJ-87189401 with JNJ-78278343 (Part 1: dose escalation) and further evaluate the safety at RP2Rs (Part 2: dose expansion) in participants with advanced prostate cancer.

What is the current status of trial NCT06095089?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 250 participants. The study started on 2023-11-01. Estimated completion is 2028-06-28.

What conditions does trial NCT06095089 study?

This clinical trial studies the following conditions: Advanced Prostate Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06095089?

The interventions under investigation include: JNJ-78278343 (DRUG), JNJ-87189401 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06095089?

This trial is sponsored by Janssen Research & Development, which has 442 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06095089 being conducted?

This trial has 6 study locations across Colorado, New York, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial