Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 2

Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease

NCT06079190 · View on ClinicalTrials.gov ↗

Study Summary

The aim of this study is to assess the efficacy and safety of GSK4527226 in participants with early Alzheimer's Disease (AD) (including mild cognitive impairment \[MCI\] and mild dementia due to AD) of 2 dose levels of GSK4527226 compared to placebo.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG GSK4527226

Study Locations (20)

Florida

  • GSK Investigational Site — Lake Mary
  • GSK Investigational Site — Lake Worth
  • GSK Investigational Site — Maitland
  • GSK Investigational Site — Miami
  • GSK Investigational Site — Orlando
  • GSK Investigational Site — Orlando
  • GSK Investigational Site — Stuart
  • GSK Investigational Site — The Villages
  • GSK Investigational Site — The Villages

California

  • GSK Investigational Site — San Diego

Georgia

  • GSK Investigational Site — Decatur

Illinois

  • GSK Investigational Site — Elk Grove Village

Missouri

  • GSK Investigational Site — Chesterfield

New Jersey

  • GSK Investigational Site — Toms River

New York

  • GSK Investigational Site — Staten Island

North Carolina

  • GSK Investigational Site — Matthews

Trial Details

FieldValue
Enrollment Target 367 participants
Start Date 2023-10-20
Est. Completion 2026-11-23
Phase Phase 2

Sponsor

GlaxoSmithKline

558 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06079190

The ClinicalTrials.gov registry entry for NCT06079190 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 367 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Alzheimer's Disease appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06079190 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Florida, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06079190 about?

NCT06079190 is a clinical study titled "Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease". The aim of this study is to assess the efficacy and safety of GSK4527226 in participants with early Alzheimer's Disease (AD) (including mild cognitive impairment \[MCI\] and mild dementia due to AD) of 2 dose levels of GSK4527226 compared to placebo.

What is the current status of trial NCT06079190?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 367 participants. The study started on 2023-10-20. Estimated completion is 2026-11-23.

What conditions does trial NCT06079190 study?

This clinical trial studies the following conditions: Alzheimer's Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06079190?

The interventions under investigation include: Placebo (OTHER), GSK4527226 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06079190?

This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06079190 being conducted?

This trial has 20 study locations across California, Florida, Georgia, Illinois, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial