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NCT06054464 · ClinicalTrials.gov registry record · Phase 1
A Study to Investigate the Effects of Acid Reducing Agents on Pharmacokinetics of PC14586 in Healthy Participants
A Phase 1 study, sponsored by PMV Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 28
- Enrollment target
NCT06054464: Completed Phase 1 study, sponsored by PMV Pharmaceuticals.
NCT06054464 is a Phase 1 study that has completed, run by PMV Pharmaceuticals. The registered enrollment target is 28 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06054464, a Phase 1 study, has completed, sponsored by PMV Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 28 participants
- Enrollment target
Study Summary
This study will assess the effect of a Proton Pump Inhibitor (PPI) (rabeprazole) on the pharmacokinetics (PK) of PC14586 and the effect of an H2-receptor antagonist (famotidine) on the PK of PC14586
Primary Outcome
Determine the Cmax of PC14586 when co-administered with rabeprazole in plasma.
Interventions
- DRUG Rabeprazole
- DRUG Famotidine
- DRUG PC14586
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2023-09-19 |
| Est. Completion | 2024-02-06 |
| Phase | Phase 1 |
What the finished NCT06054464 record still lists
NCT06054464 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower).
The record links to 0 conditions, and to 3 interventions - of which Rabeprazole is the first listed.
NCT06054464 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06054464 about?
NCT06054464 is a clinical study titled "A Study to Investigate the Effects of Acid Reducing Agents on Pharmacokinetics of PC14586 in Healthy Participants". This study will assess the effect of a Proton Pump Inhibitor (PPI) (rabeprazole) on the pharmacokinetics (PK) of PC14586 and the effect of an H2-receptor antagonist (famotidine) on the PK of PC14586
What is the current status of trial NCT06054464?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2023-09-19. Estimated completion is 2024-02-06.
What interventions are being tested in trial NCT06054464?
The interventions under investigation include: Rabeprazole (DRUG), Famotidine (DRUG), PC14586 (DRUG).
Who is sponsoring clinical trial NCT06054464?
This trial is sponsored by PMV Pharmaceuticals, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06054464's enrollment target sits among peer trials
28 1447th of 2000 higher than 538 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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