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NCT06054295 · ClinicalTrials.gov registry record

Somatic Mosaicism in Twins Discordant for Childhood Cancer

A clinical trial of Central Nervous System Tumor and Somatic Mutation, sponsored by Children's Oncology Group.

Recruiting
Registry status
50
Enrollment target
1
Study location

NCT06054295 is a study of Central Nervous System Tumor and Somatic Mutation that is actively recruiting participants, run by Children's Oncology Group. The registered enrollment target is 50 participants, below the 172-participant average among 5 other Central Nervous System Tumor trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06054295, a study of Central Nervous System Tumor and Somatic Mutation, is actively recruiting participants, sponsored by Children's Oncology Group.

RECRUITING
Registry status
50 participants
Enrollment target
1
Study location

Study Summary

Somatic mosaicism in cancer associated genes is one potential explanation for discordance in childhood cancer that has not been fully explored to date. This pilot study will focus on twins with central nervous system (CNS) tumors who are identified through the Children's Oncology Group's Project: EveryChild (PEC) registry or volunteer.

Conditions Studied

Central Nervous System Tumor Somatic Mutation Pediatric Central Nervous System Tumor Discordant Twin

Interventions

  • OTHER Questionnaire Administration
  • OTHER Biospecimen collection

Study Locations (1)

Minnesota

  • University of Minnesota - Minneapolis

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2024-06-03
Est. Completion 2027-06-30

Sponsor

Children's Oncology Group

342 total trials

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What the Registry Record Tells You About NCT06054295

The ClinicalTrials.gov registry entry for NCT06054295 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 172-participant average among 5 other Central Nervous System Tumor trials with a reported enrollment target (71% lower). The listed sponsor is Children's Oncology Group, which has 342 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Central Nervous System Tumor appearing as the primary indexed condition, and to 2 interventions - of which Questionnaire Administration is the first listed.

NCT06054295 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT06054295 about?

NCT06054295 is a clinical study titled "Somatic Mosaicism in Twins Discordant for Childhood Cancer". Somatic mosaicism in cancer associated genes is one potential explanation for discordance in childhood cancer that has not been fully explored to date. This pilot study will focus on twins with central nervous system (CNS) tumors who are identified through the Children's Oncology Group's Project: Ev...

What is the current status of trial NCT06054295?

This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2024-06-03. Estimated completion is 2027-06-30.

What conditions does trial NCT06054295 study?

This clinical trial studies the following conditions: Central Nervous System Tumor, Somatic Mutation, Pediatric Central Nervous System Tumor, Discordant Twin.

What interventions are being tested in trial NCT06054295?

The interventions under investigation include: Questionnaire Administration (OTHER), Biospecimen collection (OTHER).

Who is sponsoring clinical trial NCT06054295?

This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06054295 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.