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NCT06011109 · ClinicalTrials.gov registry record · Phase 1
Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab
A Phase 1 study of Glioblastoma Multiforme and Glioma, sponsored by Aveta Biomics.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 2
- Study locations
NCT06011109 is a Phase 1 study of Glioblastoma Multiforme and Glioma that is actively recruiting participants, run by Aveta Biomics. The registered enrollment target is 30 participants, below the 97-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (69% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT06011109, a Phase 1 study of Glioblastoma Multiforme and Glioma, is actively recruiting participants, sponsored by Aveta Biomics.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this interventional study is to evaluate the efficacy of APG-157 in combination with Bevacizumab in subjects with recurrent high-grade glioma. The main questions the study aims to answer are: * Progression-free and overall survival of patients receiving this combination; * Quality of Life (QOL); and * Tumor response on imaging The participants will take APG-157 daily by dissolving two pastilles in their mouth at around breakfast, lunch and dinner time (total of six pastilles per day). The pastilles dissolve in the mouth. The participants will continue to receive Bevacizumab as standard of care.
Conditions Studied
Interventions
- DRUG APG-157
Study Locations (2)
Minnesota
- Mayo Clinic - Rochester
Nebraska
- University of Nebraska Medical Center - Omaha
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2023-12-13 |
| Est. Completion | 2026-01-31 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06011109
The ClinicalTrials.gov registry entry for NCT06011109 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 97-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (69% lower). The listed sponsor is Aveta Biomics, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Glioblastoma Multiforme appearing as the primary indexed condition, and to 1 intervention - of which APG-157 is the first listed.
NCT06011109 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Minnesota, Nebraska.
Frequently Asked Questions
What is clinical trial NCT06011109 about?
NCT06011109 is a clinical study titled "Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab". The goal of this interventional study is to evaluate the efficacy of APG-157 in combination with Bevacizumab in subjects with recurrent high-grade glioma. The main questions the study aims to answer are: * Progression-free and overall survival of patients receiving this combination; * Quality of Li...
What is the current status of trial NCT06011109?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2023-12-13. Estimated completion is 2026-01-31.
What conditions does trial NCT06011109 study?
This clinical trial studies the following conditions: Glioblastoma Multiforme, Glioma.
What interventions are being tested in trial NCT06011109?
The interventions under investigation include: APG-157 (DRUG).
Who is sponsoring clinical trial NCT06011109?
This trial is sponsored by Aveta Biomics, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06011109 being conducted?
This trial has 2 study locations across Minnesota, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.