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NCT05994703 · ClinicalTrials.gov registry record · Phase 2

Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine

A Phase 2 study, sponsored by Rose Research Center.

Completed
Registry status
Phase 2
Development phase
25
Enrollment target

NCT05994703: Completed Phase 2 study, sponsored by Rose Research Center.

NCT05994703 is a Phase 2 study that has completed, run by Rose Research Center. The registered enrollment target is 25 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT05994703, a Phase 2 study, has completed, sponsored by Rose Research Center.

COMPLETED
Registry status
Phase 2
Development phase
25 participants
Enrollment target

Study Summary

This study will evaluate the effects of a reward devaluation strategy, which has been researched in the past, combined/augmented with the medication d-cycloserine in assisting smokers to switch from combustible cigarette (CC) to Juul.

Primary Outcome

Complete switching from combustible cigarette use at each time point will be defined by a self-report of no cigarette smoking (not even a puff) since the prior session.

Interventions

  • DRUG d-cycloserine
  • OTHER Juul e-cigarette

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2023-10-20
Est. Completion 2026-01-12
Phase Phase 2
Rose Research Center

11 total trials

What the finished NCT05994703 record still lists

NCT05994703 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower).

The record links to 0 conditions, and to 2 interventions - of which d-cycloserine is the first listed.

NCT05994703 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05994703 about?

NCT05994703 is a clinical study titled "Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine". This study will evaluate the effects of a reward devaluation strategy, which has been researched in the past, combined/augmented with the medication d-cycloserine in assisting smokers to switch from combustible cigarette (CC) to Juul.

What is the current status of trial NCT05994703?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2023-10-20. Estimated completion is 2026-01-12.

What interventions are being tested in trial NCT05994703?

The interventions under investigation include: d-cycloserine (DRUG), Juul e-cigarette (OTHER).

Who is sponsoring clinical trial NCT05994703?

This trial is sponsored by Rose Research Center, which has 11 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05994703's enrollment target sits among peer trials

25 1719th of 2000 higher than 245 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05994703, the US trial registry maintained by the National Library of Medicine. NCT05994703 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.