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NCT05989763 · ClinicalTrials.gov registry record · NA
Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis
A NA study of Constipation and Systemic Sclerosis, sponsored by The University of Texas Health Science Center, Houston.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05989763: Recruiting NA study of Constipation and Systemic Sclerosis, sponsored by The University of Texas Health Science Center, Houston.
NCT05989763 is a NA study of Constipation and Systemic Sclerosis that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 60 participants, below the 204-participant average among 54 other Constipation trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05989763, a NA study of Constipation and Systemic Sclerosis, is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine whether transcutaneous electrical acustimulation (TEA) alters systemic sclerosis (SSc)-related colonic and anorectal physiology by enhancing autonomic nervous system (ANS) function. The study will examine the effects of TEA on slow colonic transit (SCT) and rectal hyposensitivity (RH), to examine whether TEA improves autonomic dysfunction and modulates inflammatory pathways.
Primary Outcome
slow colonic transit (SCT) is defined by more than 5 (20%) of Sitz markers retained 5 days after ingestion
Conditions Studied
Interventions
- DEVICE Transcutaneous Electrical Acustimulation (TEA)
- DEVICE Sham-TEA
Study Locations (1)
Texas
- The University of Texas Health Science Center at Houston - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-02-17 |
| Est. Completion | 2029-09-01 |
| Phase | NA |
What NCT05989763 shows while recruiting
NCT05989763 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 204-participant average among 54 other Constipation trials with a reported enrollment target (71% lower).
The record links to 4 conditions, with Constipation appearing as the primary indexed condition, and to 2 interventions - of which Transcutaneous Electrical Acustimulation (TEA) is the first listed.
NCT05989763 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05989763 about?
NCT05989763 is a clinical study titled "Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis". The purpose of this study is to determine whether transcutaneous electrical acustimulation (TEA) alters systemic sclerosis (SSc)-related colonic and anorectal physiology by enhancing autonomic nervous system (ANS) function. The study will examine the effects of TEA on slow colonic transit (SCT) and ...
What is the current status of trial NCT05989763?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-02-17. Estimated completion is 2029-09-01.
What conditions does trial NCT05989763 study?
This clinical trial studies the following conditions: Constipation, Systemic Sclerosis, Autonomic Dysfunction, Gastrointestinal Motility Disorder.
What interventions are being tested in trial NCT05989763?
The interventions under investigation include: Transcutaneous Electrical Acustimulation (TEA) (DEVICE), Sham-TEA (DEVICE).
Who is sponsoring clinical trial NCT05989763?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05989763 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Constipation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05989763's enrollment target sits among peer trials
60 29th of 54 higher than 25 of 54 other Constipation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Constipation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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