Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 2

IMPACT TRIAL: Efficacy and Safety of Pemvidutide in Subjects With Nonalcoholic Steatohepatitis (NASH)

NCT05989711 · View on ClinicalTrials.gov ↗

Study Summary

Purpose of this study is to assess the effects of pemvidutide on NASH resolution and NASH fibrosis.

Interventions

  • DRUG Placebo
  • DRUG Pemvidutide

Study Locations (20)

Florida

  • Altimmune Clinical Study Site — Bradenton
  • Altimmune Clinical Study Site — Fort Myers
  • Altimmune Clinical Study Site — Hialeah Gardens
  • Altimmune Clinical Study Site — Miami Lakes
  • Altimmune Clinical Study Site — Port Orange
  • Altimmune Clinical Study Site — Sarasota
  • Altimmune Clinical Study Site — West Palm Beach

Arizona

  • Altimmune Clinical Study Site — Chandler
  • Altimmune Clinical Study Site — Peoria
  • Altimmune Clinical Study Site — Tucson
  • Altimmune Clinial Study Site — Tucson

California

  • Altimmune Clinical Study Site — North Hollywood
  • Altimmune Clinical Study Site — Panorama City

Georgia

  • Altimmune Clinical Study Site — Dalton
  • Altimmune Clinical Study Site — Marietta

Louisiana

  • Altimmune Clinical Study Site — Bastrop
  • Altimmune Clinical Study Site — Shreveport

Tennessee

  • Altimmune Clinical Study Site — Clarksville
  • Altimmune Clinical Study Site — Germantown

Colorado

  • Altimmune Clinical Study Site — Englewood

Trial Details

FieldValue
Enrollment Target 212 participants
Start Date 2023-07-27
Est. Completion 2025-11-25
Phase Phase 2

Sponsor

Altimmune

5 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05989711

The ClinicalTrials.gov registry entry for NCT05989711 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 212 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Altimmune, which has 5 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Non-Alcoholic Steatohepatitis (NASH) appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05989711 reports 20 study locations spanning 7 distinct geographic areas — top geographies include Florida, Arizona, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05989711 about?

NCT05989711 is a clinical study titled "IMPACT TRIAL: Efficacy and Safety of Pemvidutide in Subjects With Nonalcoholic Steatohepatitis (NASH)". Purpose of this study is to assess the effects of pemvidutide on NASH resolution and NASH fibrosis.

What is the current status of trial NCT05989711?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 212 participants. The study started on 2023-07-27. Estimated completion is 2025-11-25.

What conditions does trial NCT05989711 study?

This clinical trial studies the following conditions: Non-Alcoholic Steatohepatitis (NASH). These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05989711?

The interventions under investigation include: Placebo (DRUG), Pemvidutide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05989711?

This trial is sponsored by Altimmune, which has 5 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05989711 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial