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NCT05989581 · ClinicalTrials.gov registry record · Phase 1
Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot Project
A Phase 1 study of Hypertension in Pregnancy, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 74
- Enrollment target
- 1
- Study location
NCT05989581 is a Phase 1 study of Hypertension in Pregnancy that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 74 participants, below the 443-participant average among 13 other Hypertension in Pregnancy trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05989581, a Phase 1 study of Hypertension in Pregnancy, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 74 participants
- Enrollment target
- 1
- Study location
Study Summary
The CHAP2 study is designed to provide preliminary data for a larger multicenter study to assess whether treatment of stage 1 hypertension (HTN) in pregnancy improves maternal and or neonatal outcomes. The primary objective of this pilot study is to determine if anti-HTN treatment to BP\<130/80mmHg in pregnant patients with stage 1 HTN is associated with a difference in birthweight percentile at delivery. Patients with stage 1 hypertension in pregnancy will be randomized to BP goals of \<130/80mmHg or usual care to treatment only if BPs ≥140/90mmHg. For this pilot, the investigator will randomize a total of 74 eligible participants, 37 to active treatment to BP\<130/80mmHg and 37 to usual care.
Conditions Studied
Interventions
- DRUG Labetalol or Nifedipine
Study Locations (1)
Alabama
- UAB - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2024-04-24 |
| Est. Completion | 2026-06-30 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05989581
The ClinicalTrials.gov registry entry for NCT05989581 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 74 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 443-participant average among 13 other Hypertension in Pregnancy trials with a reported enrollment target (83% lower). The listed sponsor is University of Alabama at Birmingham, which has 1,160 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hypertension in Pregnancy appearing as the primary indexed condition, and to 1 intervention - of which Labetalol or Nifedipine is the first listed.
NCT05989581 reports 1 study location spanning 1 distinct geographic area - top geographies include Alabama.
Frequently Asked Questions
What is clinical trial NCT05989581 about?
NCT05989581 is a clinical study titled "Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot Project". The CHAP2 study is designed to provide preliminary data for a larger multicenter study to assess whether treatment of stage 1 hypertension (HTN) in pregnancy improves maternal and or neonatal outcomes. The primary objective of this pilot study is to determine if anti-HTN treatment to BP\<130/80mmHg ...
What is the current status of trial NCT05989581?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 74 participants. The study started on 2024-04-24. Estimated completion is 2026-06-30.
What conditions does trial NCT05989581 study?
This clinical trial studies the following conditions: Hypertension in Pregnancy.
What interventions are being tested in trial NCT05989581?
The interventions under investigation include: Labetalol or Nifedipine (DRUG).
Who is sponsoring clinical trial NCT05989581?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05989581 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.