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NCT05985928 · ClinicalTrials.gov registry record
Sensory Study: Taste and Tongue Biology
A clinical trial, sponsored by University of Massachusetts, Amherst.
- Completed
- Registry status
- 121
- Enrollment target
NCT05985928: Completed study, sponsored by University of Massachusetts, Amherst.
NCT05985928 is a clinical trial that has completed, run by University of Massachusetts, Amherst. The registered enrollment target is 121 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05985928 has completed, sponsored by University of Massachusetts, Amherst.
- COMPLETED
- Registry status
- 121 participants
- Enrollment target
Study Summary
Researchers will investigate the correlation between a) self-reported dietary intake of foods and beverages, b) intensity of sucrose stimuli, and c) liking rating of sweet stimuli, with the relative expression of the taste receptor genes from human fungiform papillae (TAS1R2 and TAS1R3). \* This research will provide new information on how sweet taste perception is regulated. * The hypothesis: Greater dietary consumption of sugar and sweet foods is associated with reduced expression of the sweet taste receptors. * The results of this study could help to identify pathways to help modify sweet taste perception by uncovering this mechanism. Participants will sample solutions prepared with sweet ingredients, provide salivary DNA, and collect fungiform papillae. This will allow researchers and investigators to compare the relationship between the sweetness of stimuli, genetic differences in sweet taste receptors, and expression levels of sweet taste receptor genes.
Primary Outcome
The relative level of gene expression of sweet taste receptors (TAS1R2 and TAS1R3) and relationship with sweet taste perception (gLMS ratings of sampled sucrose)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 121 participants |
| Start Date | 2023-03-20 |
| Est. Completion | 2025-05-20 |
What the finished NCT05985928 record still lists
NCT05985928 is an observational study that tracks outcomes without assigning an intervention. The registered 121 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT05985928 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05985928 about?
NCT05985928 is a clinical study titled "Sensory Study: Taste and Tongue Biology". Researchers will investigate the correlation between a) self-reported dietary intake of foods and beverages, b) intensity of sucrose stimuli, and c) liking rating of sweet stimuli, with the relative expression of the taste receptor genes from human fungiform papillae (TAS1R2 and TAS1R3). \* This re...
What is the current status of trial NCT05985928?
This trial is currently completed. The enrollment target is 121 participants. The study started on 2023-03-20. Estimated completion is 2025-05-20.
Who is sponsoring clinical trial NCT05985928?
This trial is sponsored by University of Massachusetts, Amherst, which has 33 total clinical trials registered on ClinicalTrials.gov.
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