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NCT05985148 · ClinicalTrials.gov registry record · Phase 1
A Study of Stereotactic Radiosurgery (SRS) to Treat Pain in the Chest and/or Stomach Wall
A Phase 1 study of Thoracoabdominal Wall Pain and Secondary to Parietal Pleura or Parietal Peritoneum Disease, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
- 7
- Study locations
NCT05985148: Recruiting Phase 1 study of Thoracoabdominal Wall Pain and Secondary to Parietal Pleura or Parietal Peritoneum Disease, sponsored by Memorial Sloan Kettering Cancer Center.
NCT05985148 is a Phase 1 study of Thoracoabdominal Wall Pain and Secondary to Parietal Pleura or Parietal Peritoneum Disease that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). The trial reports 7 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05985148, a Phase 1 study of Thoracoabdominal Wall Pain and Secondary to Parietal Pleura or Parietal Peritoneum Disease, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
- 7
- Study locations
Study Summary
The researchers are doing this study to find out whether stereotactic radiosurgery (SRS) is a safe, practical (feasible), and effective treatment for people with chronic TAWP. The researchers will test different doses of SRS to find the highest dose that causes few or mild side effects.
Primary Outcome
DLT's CTCAE grade ≥ 3 toxicity. Acute and late toxicity will be assessed by investigators and graded according to the Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0. Toxicities that cannot be graded using the Common Toxicity Criteria will be graded as 1 (mildly symptomatic), 2 (moderately symptomatic but not interfering significantly with function), 3 (causing significant interference with function), or 4 (life-threatening).
Conditions Studied
Interventions
- RADIATION Single-fraction stereotactic radiosurgery (SRS)
Study Locations (7)
New York
- Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities) - Commack
- Memorial Sloan Kettering Westchester (Limited Protocol Activities) - Harrison
- Memorial Sloan Kettering Cancer Center - New York
- Memorial Sloan Kettering Nassau (Limited Protocol Activities) - Uniondale
New Jersey
- Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) - Basking Ridge
- Memorial Sloan Kettering Monmouth (Limited Protocol Activities) - Middletown
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2023-08-02 |
| Est. Completion | 2028-08 |
| Phase | Phase 1 |
What NCT05985148 shows while recruiting
NCT05985148 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).
The record links to 2 conditions, with Thoracoabdominal Wall Pain appearing as the primary indexed condition, and to 1 intervention - of which Single-fraction stereotactic radiosurgery (SRS) is the first listed.
NCT05985148 lists 7 locations in 2 states (New York, New Jersey).
Frequently Asked Questions
What is clinical trial NCT05985148 about?
NCT05985148 is a clinical study titled "A Study of Stereotactic Radiosurgery (SRS) to Treat Pain in the Chest and/or Stomach Wall". The researchers are doing this study to find out whether stereotactic radiosurgery (SRS) is a safe, practical (feasible), and effective treatment for people with chronic TAWP. The researchers will test different doses of SRS to find the highest dose that causes few or mild side effects.
What is the current status of trial NCT05985148?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2023-08-02. Estimated completion is 2028-08.
What conditions does trial NCT05985148 study?
This clinical trial studies the following conditions: Thoracoabdominal Wall Pain, Secondary to Parietal Pleura or Parietal Peritoneum Disease.
What interventions are being tested in trial NCT05985148?
The interventions under investigation include: Single-fraction stereotactic radiosurgery (SRS) (RADIATION).
Who is sponsoring clinical trial NCT05985148?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05985148 being conducted?
This trial has 7 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05985148's enrollment target sits among peer trials
18 1721st of 2000 higher than 216 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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