Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05977946 · ClinicalTrials.gov registry record · NA
Delivering Transcutaneous Auricular Neurostimulation to Regulate Platelet Activity in Healthy Human Subjects
A NA study of Hemostasis and Blood Biomarkers, sponsored by Spark Biomedical.
- Completed
- Registry status
- NA
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT05977946 is a NA study of Hemostasis and Blood Biomarkers that has completed, run by Spark Biomedical. The registered enrollment target is 25 participants, below the 394-participant average among 7 other Hemostasis trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05977946, a NA study of Hemostasis and Blood Biomarkers, has completed, sponsored by Spark Biomedical.
- COMPLETED
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is designed as a randomized, double-blind, sham-controlled, single-center research study in which healthy adults will be randomized 1:1 into one of two experimental groups, to receive transcutaneous auricular vagus nerve stimulation (taVNS) targeting either the auricular branch of the vagus nerve (ABVN) or tAN, which targets the ABVN and the auriculotemporal nerve (ATN): 1. Group 1: Sham taVNS followed by active taVNS 2. Group 2: Sham tAN followed by active tAN Participants will receive 30 minutes of sham stimulation (taVNS or tAN), followed by active stimulation (taVNS or tAN). Blood biomarkers (local and systemic) will be measured before and at several timepoints after stimulation to measure the molecular and cellular effects of the device.
Conditions Studied
Interventions
- DEVICE Volta System
Study Locations (1)
New York
- The Feinstein Institutes for Medical Research - Manhasset
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2023-10-31 |
| Est. Completion | 2024-08-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05977946
The ClinicalTrials.gov registry entry for NCT05977946 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 394-participant average among 7 other Hemostasis trials with a reported enrollment target (94% lower). The listed sponsor is Spark Biomedical, which has 13 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Hemostasis appearing as the primary indexed condition, and to 1 intervention - of which Volta System is the first listed.
NCT05977946 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT05977946 about?
NCT05977946 is a clinical study titled "Delivering Transcutaneous Auricular Neurostimulation to Regulate Platelet Activity in Healthy Human Subjects". This study is designed as a randomized, double-blind, sham-controlled, single-center research study in which healthy adults will be randomized 1:1 into one of two experimental groups, to receive transcutaneous auricular vagus nerve stimulation (taVNS) targeting either the auricular branch of the vag...
What is the current status of trial NCT05977946?
This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2023-10-31. Estimated completion is 2024-08-06.
What conditions does trial NCT05977946 study?
This clinical trial studies the following conditions: Hemostasis, Blood Biomarkers.
What interventions are being tested in trial NCT05977946?
The interventions under investigation include: Volta System (DEVICE).
Who is sponsoring clinical trial NCT05977946?
This trial is sponsored by Spark Biomedical, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05977946 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hemostasis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Vascular Closure With a Device Compared to Manual Compression After Atrial Fibrillation Ablation: The LockeT II Study
RECRUITING · NA
-
A Study of ETHIZIA Versus SURGICEL Original in Controlling Soft Tissue Bleeding During Open Surgery
RECRUITING · NA
-
Randomized Study of Accelerated Radial Arterial Hemostasis
COMPLETED · NA
-
Efficacy and Safety of HemoStyp as an Adjunct for Management of Secondary Hemostasis in the Operative Setting
COMPLETED · NA
-
Investigation of the Genetics of Hematologic Diseases
RECRUITING
-
MANTIS Endoscopic Clipping Study
COMPLETED
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.