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NCT05976646 · ClinicalTrials.gov registry record · Phase 1
Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion
A Phase 1 study, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
NCT05976646 is a Phase 1 study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 18 participants.
The verdict
NCT05976646, a Phase 1 study, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
Study Summary
The overall goal of this project is to collect initial human data on the effects of novel compounds on safety (interactions with an opioid drug, e.g., buprenorphine) and early efficacy signals (subjective effects on negative affect, craving, and opioid withdrawal) in OUD subjects currently in MOUD treatment with buprenorphine.
Interventions
- DRUG Placebo
- DRUG Auvelity
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2023-09-18 |
| Est. Completion | 2025-07-09 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05976646
The ClinicalTrials.gov registry entry for NCT05976646 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Virginia Commonwealth University, which has 558 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05976646 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05976646 about?
NCT05976646 is a clinical study titled "Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion". The overall goal of this project is to collect initial human data on the effects of novel compounds on safety (interactions with an opioid drug, e.g., buprenorphine) and early efficacy signals (subjective effects on negative affect, craving, and opioid withdrawal) in OUD subjects currently in MOUD t...
What is the current status of trial NCT05976646?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2023-09-18. Estimated completion is 2025-07-09.
What interventions are being tested in trial NCT05976646?
The interventions under investigation include: Placebo (DRUG), Auvelity (DRUG).
Who is sponsoring clinical trial NCT05976646?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
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