Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05973747 · ClinicalTrials.gov registry record · Early Phase 1
Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in Parturients
A Early Phase 1 study, sponsored by Stanford University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 34
- Enrollment target
NCT05973747: Completed Early Phase 1 study, sponsored by Stanford University.
NCT05973747 is a Early Phase 1 study that has completed, run by Stanford University. The registered enrollment target is 34 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05973747, a Early Phase 1 study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 34 participants
- Enrollment target
Study Summary
Calcium is a life saving medicine in the care of parturients. It has many important uses including treatment of hypocalcemia, treatment of magnesium toxicity, prevention of hypocalcemia during blood transfusion (of citrate containing blood products), treatment of hyperkalemia, and others. Recent clinical trials also suggest that calcium given after cord clamping may decrease blood loss in patients undergoing cesarean delivery. 2 FDA approved forms of calcium can be given intravenously: calcium chloride and calcium gluconate. Over the last decade there have been times with drug shortages of either calcium chloride or calcium gluconate. So there have been and likely will continue to be times when one formulation or the other may not be adequately available. Despite the importance of calcium and the frequency in which it is used in parturients, there are no published studies in parturients to determine dose equivalence between calcium gluconate and calcium chloride. In this study the investigators will determine the population pharmacokinetics of calcium gluconate and calcium chloride in parturients and calculate the dose equivalent ratio the two drugs. This will help clinicians select appropriate doses of calcium and provide resilience to the drug supply chain in our era of frequent drug shortages.
Interventions
- DRUG Calcium Gluconate
- DRUG Calcium chloride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2023-08-19 |
| Est. Completion | 2023-12-15 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05973747
The ClinicalTrials.gov registry entry for NCT05973747 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Calcium Gluconate is the first listed.
NCT05973747 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05973747 about?
NCT05973747 is a clinical study titled "Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in Parturients". Calcium is a life saving medicine in the care of parturients. It has many important uses including treatment of hypocalcemia, treatment of magnesium toxicity, prevention of hypocalcemia during blood transfusion (of citrate containing blood products), treatment of hyperkalemia, and others. Recent cli...
What is the current status of trial NCT05973747?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 34 participants. The study started on 2023-08-19. Estimated completion is 2023-12-15.
What interventions are being tested in trial NCT05973747?
The interventions under investigation include: Calcium Gluconate (DRUG), Calcium chloride (DRUG).
Who is sponsoring clinical trial NCT05973747?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.