Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05953428 · ClinicalTrials.gov registry record · NA
Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia
A NA study of Hiatal Hernia, sponsored by Endeavor Health.
- Recruiting
- Registry status
- NA
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT05953428: Recruiting NA study of Hiatal Hernia, sponsored by Endeavor Health.
NCT05953428 is a NA study of Hiatal Hernia that is actively recruiting participants, run by Endeavor Health. The registered enrollment target is 75 participants, below the 882-participant average among 9 other Hiatal Hernia trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05953428, a NA study of Hiatal Hernia, is actively recruiting participants, sponsored by Endeavor Health.
- RECRUITING
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective randomized, double-blinded, controlled trial that will enroll 75 subjects undergoing laparoscopic hiatal hernia repair surgery. Participants who meet eligibility criteria will be randomized in a 1:1 ratio to receive either the opioid sparring anesthesia protocol (OSA) or the opioid based anesthesia protocol (OBA). The purpose of this study is to investigate if an opioid sparring protocol for laparoscopic hiatal hernia repair will reduce opioid consumption during discharge. Other outcomes include: postoperative VAS scores (PACU arrival, PACU discharge, hospital discharge), total in hospital opioid consumption, PACU length of stay, incidence of postoperative nausea and vomiting (PONV in PACU, postoperative day 1, during hospital stay), rehospitalization rate, rate of reoperation, rate of emergency room visit, surgeon satisfaction, and hospital cost differential.
Primary Outcome
The difference in discharge opioid consumption in morphine milligram equivalents (MMEs) from postoperative day 1 through postoperative day 7 in patients in the Opioid Sparing Anesthesia (OSA) protocol vs. Opioid Based Anesthesia (OBA) protocol will be collected.
Conditions Studied
Interventions
- OTHER Opioid Sparing Anesthesia Protocol (OSA)
- OTHER Opioid Based Anesthesia Protocol (OBA)
Study Locations (1)
Illinois
- Endeavor Health - Evanston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2023-11-14 |
| Est. Completion | 2026-02-01 |
| Phase | NA |
What NCT05953428 shows while recruiting
NCT05953428 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 882-participant average among 9 other Hiatal Hernia trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Hiatal Hernia appearing as the primary indexed condition, and to 2 interventions - of which Opioid Sparing Anesthesia Protocol (OSA) is the first listed.
NCT05953428 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT05953428 about?
NCT05953428 is a clinical study titled "Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia". This is a prospective randomized, double-blinded, controlled trial that will enroll 75 subjects undergoing laparoscopic hiatal hernia repair surgery. Participants who meet eligibility criteria will be randomized in a 1:1 ratio to receive either the opioid sparring anesthesia protocol (OSA) or the op...
What is the current status of trial NCT05953428?
This trial is currently recruiting. It is a NA study. The enrollment target is 75 participants. The study started on 2023-11-14. Estimated completion is 2026-02-01.
What conditions does trial NCT05953428 study?
This clinical trial studies the following conditions: Hiatal Hernia.
What interventions are being tested in trial NCT05953428?
The interventions under investigation include: Opioid Sparing Anesthesia Protocol (OSA) (OTHER), Opioid Based Anesthesia Protocol (OBA) (OTHER).
Who is sponsoring clinical trial NCT05953428?
This trial is sponsored by Endeavor Health, which has 94 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05953428 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hiatal Hernia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05953428's enrollment target sits among peer trials
75 7th of 9 higher than 3 of 9 other Hiatal Hernia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hiatal Hernia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Evaluating Clinical Hiatal Hernia Outcomes Using OviTex®
RECRUITING · NA
-
Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair
RECRUITING · NA
-
Multicenter Single-Blind RCT of CTIF Versus LNF For Treatment of GERD in Patients Requiring Hiatal Hernia Repair
ACTIVE NOT RECRUITING · NA
-
Esophagogastric Junction Distensibility During Hiatal Hernia Repair
ACTIVE NOT RECRUITING · NA
-
Randomized EsophyX Versus Sham / Placebo Controlled TIF Trial: The RESPECT Study
COMPLETED · NA
-
Miromatrix Biological Mesh for Hiatal Hernia Repair
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01535430 · 75 participants
Assessment of Eloquent Function in Brain Tumor Patients
- NCT01542879 · 75 participants · Phase 1
Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer
- NCT02232191 · 75 participants · Phase 2
Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients
- NCT02754544 · 75 participants · NA
Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI