Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 4

Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study

NCT05935358 · View on ClinicalTrials.gov ↗

Study Summary

Recombinant factor VIII for the prevention of bleeding in patients with severe haemophilia A undergoing major surgery while receiving emicizumab prophylaxis

Conditions Studied

Interventions

  • DRUG Nuwiq

Study Locations (18)

Other

  • University Hospital Centre Zagreb — Zagreb
  • Helsinki University Hospital — Helsinki
  • CHU de Nantes Hôtel-Dieu — Nantes
  • CHRU de Tours — Tours
  • Vivantes Klinikum im Friedrichshein (KFH) — Berlin
  • Gerinnungszentrum Rhein-Ruhr — Duisburg
  • Universitätsklinikum Hamburg Eppendorf (UKE) — Hamburg
  • St. John's Medical College Hospital — Bengaluru
  • Azienda Ospedaliera Pugliese Ciaccio — Catanzaro
  • Azienda Ospedaliero Universitaria Careggi - Centro Emofilia — Florence
  • Centro Trombosi e Malattie Emorragiche, ITCCS Humanitas Research Hospital — Milan
  • Centre for Haemopilia, Institute for transfusion medicine of Republic of North Macedonia — Skopje
  • Clinical Center for Serbia Belgrade — Belgrade
  • Hospital Universitario La Paz — Madrid
  • Hospital Universitario Virgen del Rocio — Seville
  • St. James's University Hospital — Leeds

Texas

  • UT Southwestern Medical Center — Dallas

Tamil Nadu

  • Christian Medical College Vellore — Vellore

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2023-11-28
Est. Completion 2026-08
Phase Phase 4

Sponsor

Octapharma

73 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05935358

The ClinicalTrials.gov registry entry for NCT05935358 describes a study currently listed as recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Octapharma, which has 73 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Severe Hemophilia A appearing as the primary indexed condition, and to 1 intervention — of which Nuwiq is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05935358 reports 18 study locations spanning 3 distinct geographic areas — top geographies include Other, Texas, Tamil Nadu. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05935358 about?

NCT05935358 is a clinical study titled "Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study". Recombinant factor VIII for the prevention of bleeding in patients with severe haemophilia A undergoing major surgery while receiving emicizumab prophylaxis

What is the current status of trial NCT05935358?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 28 participants. The study started on 2023-11-28. Estimated completion is 2026-08.

What conditions does trial NCT05935358 study?

This clinical trial studies the following conditions: Severe Hemophilia A. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05935358?

The interventions under investigation include: Nuwiq (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05935358?

This trial is sponsored by Octapharma, which has 73 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05935358 being conducted?

This trial has 18 study locations across Texas, Tamil Nadu. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial