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NCT05933681 · ClinicalTrials.gov registry record · NA
Neurophysiology Biomarkers of Cognitive Impairment Associated With Deep Brain Stimulation
A NA study of Parkinson Disease, sponsored by Vanderbilt University Medical Center.
- Active
- Registry status
- NA
- Development phase
- 160
- Enrollment target
- 1
- Study location
NCT05933681: Active NA study of Parkinson Disease, sponsored by Vanderbilt University Medical Center.
NCT05933681 is a NA study of Parkinson Disease that is active but no longer recruiting, run by Vanderbilt University Medical Center. The registered enrollment target is 160 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05933681, a NA study of Parkinson Disease, is active but no longer recruiting, sponsored by Vanderbilt University Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 160 participants
- Enrollment target
- 1
- Study location
Study Summary
The study aims to investigate cognitive impairment associated with Deep Brain Stimulation (DBS) in Parkinson's Disease patients, with a focus on identifying neurophysiology biomarkers of DBS associated cognitive changes. Using neurophysiology data recorded during DBS surgeries and post-implantation, the research intends to identify biomarkers in order to optimize electrode placement, enhance programming, and ultimately minimize DBS-related cognitive side effects.
Primary Outcome
Working memory tasked will be conducted during surgery, and local field potentials (LFPs) will be recorded from the DLPFC both at rest and during task execution, under two conditions: with and without stimulation.
Conditions Studied
Interventions
- DEVICE Neural recordings and stimulation
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2023-07-06 |
| Est. Completion | 2026-05-30 |
| Phase | NA |
What the registry record for NCT05933681 still lists
NCT05933681 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Parkinson Disease appearing as the primary indexed condition, and to 1 intervention - of which Neural recordings and stimulation is the first listed.
NCT05933681 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT05933681 about?
NCT05933681 is a clinical study titled "Neurophysiology Biomarkers of Cognitive Impairment Associated With Deep Brain Stimulation". The study aims to investigate cognitive impairment associated with Deep Brain Stimulation (DBS) in Parkinson's Disease patients, with a focus on identifying neurophysiology biomarkers of DBS associated cognitive changes. Using neurophysiology data recorded during DBS surgeries and post-implantation,...
What is the current status of trial NCT05933681?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 160 participants. The study started on 2023-07-06. Estimated completion is 2026-05-30.
What conditions does trial NCT05933681 study?
This clinical trial studies the following conditions: Parkinson Disease.
What interventions are being tested in trial NCT05933681?
The interventions under investigation include: Neural recordings and stimulation (DEVICE).
Who is sponsoring clinical trial NCT05933681?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05933681 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05933681's enrollment target sits among peer trials
160 52nd of 297 higher than 246 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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