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NCT05913401 · ClinicalTrials.gov registry record · NA
Exercise to Augment TMS in Those With Treatment Resistant Depression
A NA study of Treatment-Resistant Depression, sponsored by Butler Hospital.
- Active
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05913401: Active NA study of Treatment-Resistant Depression, sponsored by Butler Hospital.
NCT05913401 is a NA study of Treatment-Resistant Depression that is active but no longer recruiting, run by Butler Hospital. The registered enrollment target is 30 participants, below the 373-participant average among 54 other Treatment-Resistant Depression trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05913401, a NA study of Treatment-Resistant Depression, is active but no longer recruiting, sponsored by Butler Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Given the growing evidence that aerobic increases cortical excitability and promotes neuroplasticity, the scientific premise for its potential priming effect on the brain is strong. Combining AE with rTMS may produce a neural environment optimized for a robust physiological effect of rTMS, thereby leading to improved depression outcomes. With positive findings, this study would provide preliminary support for an innovative, safe and feasible approach for improving outcomes for this significant public health problem.
Primary Outcome
Percentage of participants approached for the study who agree to participate
Conditions Studied
Interventions
- BEHAVIORAL Aerobic Exercise
- BEHAVIORAL Video Watching
Study Locations (1)
Rhode Island
- Butler Hospital - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2024-02-01 |
| Est. Completion | 2025-12-31 |
| Phase | NA |
What the registry record for NCT05913401 still lists
NCT05913401 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 373-participant average among 54 other Treatment-Resistant Depression trials with a reported enrollment target (92% lower).
The record links to 1 condition, with Treatment-Resistant Depression appearing as the primary indexed condition, and to 2 interventions - of which Aerobic Exercise is the first listed.
NCT05913401 reports a single indexed study location in Rhode Island.
Frequently Asked Questions
What is clinical trial NCT05913401 about?
NCT05913401 is a clinical study titled "Exercise to Augment TMS in Those With Treatment Resistant Depression". Given the growing evidence that aerobic increases cortical excitability and promotes neuroplasticity, the scientific premise for its potential priming effect on the brain is strong. Combining AE with rTMS may produce a neural environment optimized for a robust physiological effect of rTMS, thereby l...
What is the current status of trial NCT05913401?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2024-02-01. Estimated completion is 2025-12-31.
What conditions does trial NCT05913401 study?
This clinical trial studies the following conditions: Treatment-Resistant Depression.
What interventions are being tested in trial NCT05913401?
The interventions under investigation include: Aerobic Exercise (BEHAVIORAL), Video Watching (BEHAVIORAL).
Who is sponsoring clinical trial NCT05913401?
This trial is sponsored by Butler Hospital, which has 103 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05913401 being conducted?
This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Treatment-Resistant Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05913401's enrollment target sits among peer trials
30 38th of 54 higher than 17 of 54 other Treatment-Resistant Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Treatment-Resistant Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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