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NCT05903859 · ClinicalTrials.gov registry record · Phase 3
Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
A Phase 3 study of Infertility, Male, sponsored by University of Miami.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 90
- Enrollment target
- 1
- Study location
NCT05903859: Recruiting Phase 3 study of Infertility, Male, sponsored by University of Miami.
NCT05903859 is a Phase 3 study of Infertility, Male that is actively recruiting participants, run by University of Miami. The registered enrollment target is 90 participants, below the 566-participant average among 8 other Infertility, Male trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05903859, a Phase 3 study of Infertility, Male, is actively recruiting participants, sponsored by University of Miami.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a study of infertility which often occurs in men with spinal cord injury. Most men with spinal cord injury have a normal sperm count but abnormally low sperm motility - which means that the sperm does not swim well. This study will determine if a medicine given by mouth will improve sperm motility in men with spinal cord injuries. The medicine is called probenecid.
Primary Outcome
The total sperm count will be assessed by calculating semen volume times sperm count times sperm motility percentage.The unit of measurement is in Millions.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Probenecid 500 Milligrams (mg)
- DRUG probenecid 250 Milligrams (mg)
Study Locations (1)
Florida
- University of Miami - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2024-01-18 |
| Est. Completion | 2028-12-31 |
| Phase | Phase 3 |
What NCT05903859 shows while recruiting
NCT05903859 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 566-participant average among 8 other Infertility, Male trials with a reported enrollment target (84% lower).
The record links to 1 condition, with Infertility, Male appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT05903859 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT05903859 about?
NCT05903859 is a clinical study titled "Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)". This is a study of infertility which often occurs in men with spinal cord injury. Most men with spinal cord injury have a normal sperm count but abnormally low sperm motility - which means that the sperm does not swim well. This study will determine if a medicine given by mouth will improve sperm mo...
What is the current status of trial NCT05903859?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 90 participants. The study started on 2024-01-18. Estimated completion is 2028-12-31.
What conditions does trial NCT05903859 study?
This clinical trial studies the following conditions: Infertility, Male.
What interventions are being tested in trial NCT05903859?
The interventions under investigation include: Placebo (DRUG), Probenecid 500 Milligrams (mg) (DRUG), probenecid 250 Milligrams (mg) (DRUG).
Who is sponsoring clinical trial NCT05903859?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05903859 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Infertility, Male
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05903859's enrollment target sits among peer trials
90 5th of 8 higher than 4 of 8 other Infertility, Male trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Infertility, Male trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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