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NCT04452305 · ClinicalTrials.gov registry record · NA
Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting
A NA study of Cancer and Infertility, Male, sponsored by University of Pittsburgh.
- Recruiting
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT04452305: Recruiting NA study of Cancer and Infertility, Male, sponsored by University of Pittsburgh.
NCT04452305 is a NA study of Cancer and Infertility, Male that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 10 participants, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04452305, a NA study of Cancer and Infertility, Male, is actively recruiting participants, sponsored by University of Pittsburgh.
- RECRUITING
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy. The purpose of this study is to test the safety and feasibility of these transplant technologies and restore fertility for these participants.
Primary Outcome
Rate of participants where sperm was found in semen analysis or testicular tissue analysis
Conditions Studied
Interventions
- PROCEDURE Spermatogonial Stem Cell Transplant and Testicular Tissue Grafting
Study Locations (1)
Pennsylvania
- Magee-Womens Hospital - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2023-11-10 |
| Est. Completion | 2028-07-01 |
| Phase | NA |
What NCT04452305 shows while recruiting
NCT04452305 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Cancer appearing as the primary indexed condition, and to 1 intervention - of which Spermatogonial Stem Cell Transplant and Testicular Tissue Grafting is the first listed.
NCT04452305 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04452305 about?
NCT04452305 is a clinical study titled "Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting". Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy. The purpose of this study is to test the safety and feasibility of these transpla...
What is the current status of trial NCT04452305?
This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2023-11-10. Estimated completion is 2028-07-01.
What conditions does trial NCT04452305 study?
This clinical trial studies the following conditions: Cancer, Infertility, Male, Autoimmune Disorder.
What interventions are being tested in trial NCT04452305?
The interventions under investigation include: Spermatogonial Stem Cell Transplant and Testicular Tissue Grafting (PROCEDURE).
Who is sponsoring clinical trial NCT04452305?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04452305 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04452305's enrollment target sits among peer trials
10 601st of 615 higher than 10 of 615 other Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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