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NCT05881863 · ClinicalTrials.gov registry record
To Investigate Airway Oxygen Concentrations During Rigid Bronchoscopy Procedures Performed With High Frequency Jet Ventilation
A clinical trial of Central Airway Obstruction, sponsored by University of Minnesota.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT05881863: Recruiting study of Central Airway Obstruction, sponsored by University of Minnesota.
NCT05881863 is a study of Central Airway Obstruction that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 50 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05881863, a study of Central Airway Obstruction, is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Thermal ablation (use of treatment modalities that generate heat) has become a widely used tool for treatment of central airway obstruction (e.g. laser, electrocautery, radiofrequency, and argon plasma coagulation). However, this method carries with it an increased risk for airway fire - a surgical fire that occurs in a patient's airway and could also include a fire in the attached breathing circuit. To decrease the risk of airway fire during mechanical ventilation with an endotracheal tube, the concentration of inspired oxygen (FiO2) is set below 40% while waiting for end tidal oxygen concentration (EtO2) to fall below 40% prior to starting thermal ablation. There is no published literature describing O2 concentration within the airways (AiO2) during jet ventilation with rigid bronchoscopy. The co-investigators of this study have recently collected data on AiO2 during rigid bronchoscopy using manual low frequency jet ventilation/high frequency jet ventilation with a period of apnea. The intent of this study is to measure the time taken for the central airway oxygen concentration to drop from 90 to 40% when the "laser mode" is activated on the Monsoon jet ventilator. Ventilation is continued during "laser mode."
Primary Outcome
Time in seconds to AiO2 from 90 to 40% after activating laser mode on the monsoon jet ventilator.
Conditions Studied
Interventions
- OTHER No intervention
Study Locations (1)
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-01-12 |
| Est. Completion | 2026-12-31 |
What NCT05881863 shows while recruiting
NCT05881863 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target.
The record links to 1 condition, with Central Airway Obstruction appearing as the primary indexed condition, and to 1 intervention - of which No intervention is the first listed.
NCT05881863 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT05881863 about?
NCT05881863 is a clinical study titled "To Investigate Airway Oxygen Concentrations During Rigid Bronchoscopy Procedures Performed With High Frequency Jet Ventilation". Thermal ablation (use of treatment modalities that generate heat) has become a widely used tool for treatment of central airway obstruction (e.g. laser, electrocautery, radiofrequency, and argon plasma coagulation). However, this method carries with it an increased risk for airway fire - a surgical ...
What is the current status of trial NCT05881863?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2024-01-12. Estimated completion is 2026-12-31.
What conditions does trial NCT05881863 study?
This clinical trial studies the following conditions: Central Airway Obstruction.
What interventions are being tested in trial NCT05881863?
The interventions under investigation include: No intervention (OTHER).
Who is sponsoring clinical trial NCT05881863?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05881863 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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